Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 13.64
Human Site: T57 Identified Species: 21.43
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 T57 A V C Q V T S T P D K Q Q N F
Chimpanzee Pan troglodytes XP_001152578 327 35808 T57 A V C Q V T S T P D K Q Q N F
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 T57 A V C Q V T S T P D K Q Q N F
Dog Lupus familis XP_536134 334 36663 T64 A V C Q V T S T P D K Q E N F
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 Q57 V T S T P N K Q E N F K T C A
Rat Rattus norvegicus Q7TQ94 292 32072 A47 T R L G A C L A F L P E A F D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 A31 A C K L I K E A A Q K G A Q I
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 A32 Q T L V K E A A G Q G A K V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 V57 L S Q V I E L V D R A K S Q N
Honey Bee Apis mellifera XP_397291 304 34596 R57 L S E K A K H R A A S I A F F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 C38 R R V V E T A C K M G A K M V
Poplar Tree Populus trichocarpa XP_002316330 293 31915 K48 A T C S R L V K E A V A E G A
Maize Zea mays NP_001141322 288 31722 V43 K E A A A S G V K F L C F P E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 A59 S S F K F P Y A L V R E A H A
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 R58 S Q N P L H S R Y L A Q K S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 100 93.3 N.A. 0 0 N.A. N.A. N.A. 13.3 0 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 13.3 6.6 N.A. N.A. N.A. 20 13.3 N.A. 13.3 13.3 N.A. 20
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 13.3 0 N.A. 0 13.3 N.A.
P-Site Similarity: 20 6.6 N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 7 7 20 0 14 27 14 14 14 20 27 0 20 % A
% Cys: 0 7 34 0 0 7 0 7 0 0 0 7 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 27 0 0 0 0 7 % D
% Glu: 0 7 7 0 7 14 7 0 14 0 0 14 14 0 7 % E
% Phe: 0 0 7 0 7 0 0 0 7 7 7 0 7 14 34 % F
% Gly: 0 0 0 7 0 0 7 0 7 0 14 7 0 7 0 % G
% His: 0 0 0 0 0 7 7 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 14 0 0 0 0 0 0 7 0 0 7 % I
% Lys: 7 0 7 14 7 14 7 7 14 0 34 14 20 0 0 % K
% Leu: 14 0 14 7 7 7 14 0 7 14 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % M
% Asn: 0 0 7 0 0 7 0 0 0 7 0 0 0 27 7 % N
% Pro: 0 0 0 7 7 7 0 0 27 0 7 0 0 7 7 % P
% Gln: 7 7 7 27 0 0 0 7 0 14 0 34 20 14 0 % Q
% Arg: 7 14 0 0 7 0 0 14 0 7 7 0 0 0 0 % R
% Ser: 14 20 7 7 0 7 34 0 0 0 7 0 7 7 0 % S
% Thr: 7 20 0 7 0 34 0 27 0 0 0 0 7 0 0 % T
% Val: 7 27 7 20 27 0 7 14 0 7 7 0 0 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _