Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 20
Human Site: Y113 Identified Species: 31.43
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 Y113 G G K L L E E Y T Q L A R E C
Chimpanzee Pan troglodytes XP_001152578 327 35808 Y113 G G K L L E E Y T Q L A R E C
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 Y113 G G R L L E E Y T R L A R E C
Dog Lupus familis XP_536134 334 36663 Y120 G G N L L G E Y T Q L A R E C
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 Y109 N G D L L G Q Y S Q L A R E C
Rat Rattus norvegicus Q7TQ94 292 32072 G86 S Q L A R E C G I W L S L G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 S70 G E S T E L L S Q V A K E C G
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 E71 E S T Q V L S E T A K K C G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 Y99 D G E L M A Q Y R E L A K C N
Honey Bee Apis mellifera XP_397291 304 34596 A97 V T S Y K E I A K I N K I W L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 K77 G P T I S A F K Q L A R D H K
Poplar Tree Populus trichocarpa XP_002316330 293 31915 Q87 P L D G P I M Q Q Y C S L A R
Maize Zea mays NP_001141322 288 31722 K82 Q R Y C S L A K E S S M W L S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 H101 R A K P Y K N H P T I A R M Q
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 D100 H L P P S E Q D L L E G N D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 86.6 86.6 N.A. 66.6 13.3 N.A. N.A. N.A. 6.6 6.6 N.A. 33.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 80 20 N.A. N.A. N.A. 6.6 13.3 N.A. 66.6 6.6 N.A. 13.3
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 0 0 N.A. 20 6.6 N.A.
P-Site Similarity: 6.6 0 N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 14 7 7 0 7 14 47 0 7 0 % A
% Cys: 0 0 0 7 0 0 7 0 0 0 7 0 7 14 34 % C
% Asp: 7 0 14 0 0 0 0 7 0 0 0 0 7 7 0 % D
% Glu: 7 7 7 0 7 40 27 7 7 7 7 0 7 34 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 40 40 0 7 0 14 0 7 0 0 0 7 0 14 14 % G
% His: 7 0 0 0 0 0 0 7 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 7 0 7 7 0 7 7 7 0 7 0 7 % I
% Lys: 0 0 20 0 7 7 0 14 7 0 7 20 7 0 7 % K
% Leu: 0 14 7 40 34 20 7 0 7 14 47 0 14 7 7 % L
% Met: 0 0 0 0 7 0 7 0 0 0 0 7 0 7 0 % M
% Asn: 7 0 7 0 0 0 7 0 0 0 7 0 7 0 7 % N
% Pro: 7 7 7 14 7 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 7 7 0 7 0 0 20 7 20 27 0 0 0 0 7 % Q
% Arg: 7 7 7 0 7 0 0 0 7 7 0 7 40 0 14 % R
% Ser: 7 7 14 0 20 0 7 7 7 7 7 14 0 0 7 % S
% Thr: 0 7 14 7 0 0 0 0 34 7 0 0 0 0 0 % T
% Val: 7 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 7 7 0 % W
% Tyr: 0 0 7 7 7 0 0 40 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _