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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 20.61
Human Site: Y143 Identified Species: 32.38
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 Y143 W E Q T Q K I Y N C H V L L N
Chimpanzee Pan troglodytes XP_001152578 327 35808 Y143 W E Q T Q K I Y N C H V L L N
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 Y143 W E Q T Q K I Y N C H V L L N
Dog Lupus familis XP_536134 334 36663 Y150 W E Q T Q K I Y N C H V L L N
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 Y139 W E Q N Q K I Y N C H V L L N
Rat Rattus norvegicus Q7TQ94 292 32072 S116 N C H V L L N S K G S V V A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 F100 F Y N T C A V F G P D G T L L
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 G101 Y N T C S V F G P D G T L L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 L129 K I F N A H V L L N E K G E L
Honey Bee Apis mellifera XP_397291 304 34596 I127 I S N T H I L I N S E G E I V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 H107 D L K M L N T H V I L D E N G
Poplar Tree Populus trichocarpa XP_002316330 293 31915 N117 S D D E H L R N T H V I I D D
Maize Zea mays NP_001141322 288 31722 D112 N T H V L I D D T G K V R S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 Y131 E E A N T A H Y N S I A I I D
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 L130 Q E Y Q K L H L F D V D V P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 100 100 N.A. 93.3 6.6 N.A. N.A. N.A. 13.3 13.3 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 20 N.A. N.A. N.A. 33.3 20 N.A. 6.6 26.6 N.A. 13.3
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 0 6.6 N.A. 20 13.3 N.A.
P-Site Similarity: 26.6 13.3 N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 14 0 0 0 0 0 7 0 7 0 % A
% Cys: 0 7 0 7 7 0 0 0 0 34 0 0 0 0 0 % C
% Asp: 7 7 7 0 0 0 7 7 0 14 7 14 0 7 14 % D
% Glu: 7 47 0 7 0 0 0 0 0 0 14 0 14 7 0 % E
% Phe: 7 0 7 0 0 0 7 7 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 7 14 7 14 7 0 7 % G
% His: 0 0 14 0 14 7 14 7 0 7 34 0 0 0 0 % H
% Ile: 7 7 0 0 0 14 34 7 0 7 7 7 14 14 0 % I
% Lys: 7 0 7 0 7 34 0 0 7 0 7 7 0 0 0 % K
% Leu: 0 7 0 0 20 20 7 14 7 0 7 0 40 47 14 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 14 7 14 20 0 7 7 7 47 7 0 0 0 7 40 % N
% Pro: 0 0 0 0 0 0 0 0 7 7 0 0 0 7 0 % P
% Gln: 7 0 34 7 34 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % R
% Ser: 7 7 0 0 7 0 0 7 0 14 7 0 0 7 14 % S
% Thr: 0 7 7 40 7 0 7 0 14 0 0 7 7 0 0 % T
% Val: 0 0 0 14 0 7 14 0 7 0 14 47 14 0 14 % V
% Trp: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 7 0 0 0 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _