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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 25.15
Human Site: Y269 Identified Species: 39.52
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 Y269 H H E K R A S Y G H S M V V D
Chimpanzee Pan troglodytes XP_001152578 327 35808 Y269 H H E K R A S Y G H S M V V D
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 Y269 H H E K R A S Y G H S M V V D
Dog Lupus familis XP_536134 334 36663 Y276 H H E K R A S Y G H S M V V D
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 Y265 H H E T R A S Y G H S M V V D
Rat Rattus norvegicus Q7TQ94 292 32072 V239 A S Y G H S M V V D P W G T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 T223 Y V A W G H S T V V S P W G E
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 V224 V A W G H S S V I N P W G E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 K346 T N L R C V V K G H V L V S T
Honey Bee Apis mellifera XP_397291 304 34596 A251 K R V S W G H A M V I D P W G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 Y230 H N D K R A S Y G H A M I V D
Poplar Tree Populus trichocarpa XP_002316330 293 31915 E240 G E H N D K R E S Y G D T L I
Maize Zea mays NP_001141322 288 31722 I235 E S Y G D S I I I D P W G T V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 Y265 G P S Q I T F Y G T S F I A G
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 W253 K S S R R E S W G H S M V I D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 100 100 N.A. 93.3 0 N.A. N.A. N.A. 13.3 6.6 N.A. 20 0 N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 6.6 N.A. N.A. N.A. 26.6 20 N.A. 40 0 N.A. 100
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 0 0 N.A. 20 53.3 N.A.
P-Site Similarity: 13.3 6.6 N.A. 33.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 0 40 0 7 0 0 7 0 0 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 14 0 0 0 0 14 0 14 0 0 47 % D
% Glu: 7 7 34 0 0 7 0 7 0 0 0 0 0 7 7 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % F
% Gly: 14 0 0 20 7 7 0 0 60 0 7 0 20 7 14 % G
% His: 40 34 7 0 14 7 7 0 0 54 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 7 7 14 0 7 0 14 7 7 % I
% Lys: 14 0 0 34 0 7 0 7 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 0 0 0 0 0 0 0 7 0 7 0 % L
% Met: 0 0 0 0 0 0 7 0 7 0 0 47 0 0 0 % M
% Asn: 0 14 0 7 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 20 7 7 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 14 47 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 20 14 7 0 20 60 0 7 0 54 0 0 7 0 % S
% Thr: 7 0 0 7 0 7 0 7 0 7 0 0 7 14 7 % T
% Val: 7 7 7 0 0 7 7 14 14 14 7 0 47 40 20 % V
% Trp: 0 0 7 7 7 0 0 7 0 0 0 20 7 7 0 % W
% Tyr: 7 0 14 0 0 0 0 47 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _