Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 17.27
Human Site: Y300 Identified Species: 27.14
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 Y300 L A R I D L N Y L R Q L R R H
Chimpanzee Pan troglodytes XP_001152578 327 35808 Y300 L A R I D L N Y L R Q L R Q H
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 Y300 L A R I D L S Y L R Q L R Q H
Dog Lupus familis XP_536134 334 36663 Y307 L A R I D L N Y L R Q L R Q H
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 F296 L A R I D L H F L Q Q M R Q H
Rat Rattus norvegicus Q7TQ94 292 32072 R270 L H F L Q Q M R Q H L P V F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 I254 D L Q Y L A E I R E Q I P I R
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 R255 L Q Y L A D V R Q Q I P I T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 L377 D M F T T V C L V Q R L L E K
Honey Bee Apis mellifera XP_397291 304 34596 Q282 I D L N L L K Q I R Q N M P C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 Y261 V A Q I D P D Y L Q K I R T S
Poplar Tree Populus trichocarpa XP_002316330 293 31915 I271 T G I A V A D I D F S L I D S
Maize Zea mays NP_001141322 288 31722 A266 L D L S K V E A V R T R M P I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 D296 L V A Q F D L D M I K S K R Q
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 D284 Q L I L A D L D R E L L Q E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 93.3 86.6 93.3 N.A. 66.6 6.6 N.A. N.A. N.A. 6.6 6.6 N.A. 6.6 20 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. N.A. 20 20 N.A. 33.3 33.3 N.A. 80
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 6.6 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: 13.3 26.6 N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 7 7 14 14 0 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % C
% Asp: 14 14 0 0 40 20 14 14 7 0 0 0 0 7 0 % D
% Glu: 0 0 0 0 0 0 14 0 0 14 0 0 0 14 0 % E
% Phe: 0 0 14 0 7 0 0 7 0 7 0 0 0 7 0 % F
% Gly: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 7 0 0 0 0 7 0 0 7 0 0 0 0 34 % H
% Ile: 7 0 14 40 0 0 0 14 7 7 7 14 14 7 14 % I
% Lys: 0 0 0 0 7 0 7 0 0 0 14 0 7 0 14 % K
% Leu: 60 14 14 20 14 40 14 7 40 0 14 47 7 0 0 % L
% Met: 0 7 0 0 0 0 7 0 7 0 0 7 14 0 0 % M
% Asn: 0 0 0 7 0 0 20 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 0 0 14 7 14 0 % P
% Gln: 7 7 14 7 7 7 0 7 14 27 47 0 7 27 14 % Q
% Arg: 0 0 34 0 0 0 0 14 14 40 7 7 40 14 7 % R
% Ser: 0 0 0 7 0 0 7 0 0 0 7 7 0 0 14 % S
% Thr: 7 0 0 7 7 0 0 0 0 0 7 0 0 14 0 % T
% Val: 7 7 0 0 7 14 7 0 14 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 0 0 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _