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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 24.24
Human Site: Y319 Identified Species: 38.1
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 Y319 Q H R R P D L Y G N L G H P L
Chimpanzee Pan troglodytes XP_001152578 327 35808 Y319 Q H R R P D L Y G N L G H P L
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 Y319 Q H R R P D L Y G N L G H P L
Dog Lupus familis XP_536134 334 36663 Y326 Q H R R P D L Y G N L G H P L
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 Y315 Q H R R P D L Y G S L G H P L
Rat Rattus norvegicus Q7TQ94 292 32072 G285 H R R P D L Y G S L G L P L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 Y269 R Q R R D N L Y T V E E K K N
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 S270 Q R R N D L Y S V N S V Q E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 L417 F H I M P R R L G D F G H N D
Honey Bee Apis mellifera XP_397291 304 34596 L297 E N H R R T D L Y P K L E P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 R276 M P V W N H R R N D L Y P Q F
Poplar Tree Populus trichocarpa XP_002316330 293 31915 A286 V R A K I P I A K V T L S C S
Maize Zea mays NP_001141322 288 31722 S281 S E H R K F D S D W K P T P L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 Y316 R D R R P D L Y K V L L T M D
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 N299 R N K M P L W N Q R R D D L F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 100 100 N.A. 93.3 6.6 N.A. N.A. N.A. 26.6 20 N.A. 33.3 20 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. N.A. 40 20 N.A. 40 33.3 N.A. 13.3
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 0 20 N.A. 46.6 6.6 N.A.
P-Site Similarity: 13.3 20 N.A. 53.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 7 0 0 20 40 14 0 7 14 0 7 7 0 14 % D
% Glu: 7 7 0 0 0 0 0 0 0 0 7 7 7 7 0 % E
% Phe: 7 0 0 0 0 7 0 0 0 0 7 0 0 0 14 % F
% Gly: 0 0 0 0 0 0 0 7 40 0 7 40 0 0 7 % G
% His: 7 40 14 0 0 7 0 0 0 0 0 0 40 0 0 % H
% Ile: 0 0 7 0 7 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 7 7 0 0 0 14 0 14 0 7 7 0 % K
% Leu: 0 0 0 0 0 20 47 14 0 7 47 27 0 14 47 % L
% Met: 7 0 0 14 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 14 0 7 7 7 0 7 7 34 0 0 0 7 7 % N
% Pro: 0 7 0 7 54 7 0 0 0 7 0 7 14 47 0 % P
% Gln: 40 7 0 0 0 0 0 0 7 0 0 0 7 7 0 % Q
% Arg: 20 20 60 60 7 7 14 7 0 7 7 0 0 0 0 % R
% Ser: 7 0 0 0 0 0 0 14 7 7 7 0 7 0 14 % S
% Thr: 0 0 0 0 0 7 0 0 7 0 7 0 14 0 0 % T
% Val: 7 0 7 0 0 0 0 0 7 20 0 7 0 0 0 % V
% Trp: 0 0 0 7 0 0 7 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 14 47 7 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _