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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMMD2
All Species:
29.39
Human Site:
T57
Identified Species:
64.67
UniProt:
Q86X83
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X83
NP_057178.2
199
22745
T57
K
L
N
V
S
S
D
T
V
Q
H
G
V
E
G
Chimpanzee
Pan troglodytes
XP_516817
199
22685
T57
K
L
N
V
S
S
D
T
V
Q
H
G
V
E
G
Rhesus Macaque
Macaca mulatta
XP_001108551
199
22785
T57
K
L
N
V
S
S
D
T
V
Q
H
G
V
E
G
Dog
Lupus familis
XP_542834
199
22751
T57
K
L
S
V
S
S
D
T
V
Q
H
G
V
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXC6
199
22830
T57
K
L
N
V
S
S
D
T
I
Q
H
G
V
E
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516986
150
17315
E14
D
T
V
Q
H
G
V
E
G
L
T
Y
L
L
T
Chicken
Gallus gallus
XP_422846
199
22283
T57
K
L
N
A
G
V
D
T
V
Q
H
G
V
E
G
Frog
Xenopus laevis
NP_001085231
199
22908
T57
K
L
E
V
S
S
T
T
I
Q
Q
A
V
E
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650695
233
26312
Q62
G
S
P
E
A
V
Q
Q
A
V
E
A
L
I
S
Honey Bee
Apis mellifera
XP_001120781
202
23446
L57
K
L
E
V
E
V
N
L
I
K
N
S
V
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781013
199
22668
T57
K
L
N
V
D
A
E
T
V
K
H
G
V
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.9
95.4
N.A.
93.9
N.A.
N.A.
66.3
77.8
76.8
N.A.
N.A.
30.8
40
N.A.
60.3
Protein Similarity:
100
99.5
99.5
98.9
N.A.
98.4
N.A.
N.A.
71.3
84.9
86.4
N.A.
N.A.
51.5
63.8
N.A.
74.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
0
80
66.6
N.A.
N.A.
0
40
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
80
73.3
N.A.
N.A.
13.3
66.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
10
0
0
10
0
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
55
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
19
10
10
0
10
10
0
0
10
0
0
82
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
10
0
0
10
0
0
64
0
0
82
% G
% His:
0
0
0
0
10
0
0
0
0
0
64
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
28
0
0
0
0
10
0
% I
% Lys:
82
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% K
% Leu:
0
82
0
0
0
0
0
10
0
10
0
0
19
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
55
0
0
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
10
0
64
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
55
55
0
0
0
0
0
10
0
0
10
% S
% Thr:
0
10
0
0
0
0
10
73
0
0
10
0
0
0
10
% T
% Val:
0
0
10
73
0
28
10
0
55
10
0
0
82
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _