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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMMD2
All Species:
31.52
Human Site:
Y124
Identified Species:
69.33
UniProt:
Q86X83
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X83
NP_057178.2
199
22745
Y124
L
A
P
S
L
P
S
Y
H
N
L
E
W
R
L
Chimpanzee
Pan troglodytes
XP_516817
199
22685
Y124
L
A
P
S
L
P
S
Y
H
N
L
E
W
R
L
Rhesus Macaque
Macaca mulatta
XP_001108551
199
22785
Y124
L
A
P
S
L
P
S
Y
H
N
L
E
W
R
L
Dog
Lupus familis
XP_542834
199
22751
Y124
L
S
P
D
L
P
S
Y
H
S
L
E
W
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXC6
199
22830
Y124
L
A
P
R
L
P
S
Y
H
S
L
E
W
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516986
150
17315
R81
S
Y
H
N
L
E
W
R
L
D
V
Q
L
A
S
Chicken
Gallus gallus
XP_422846
199
22283
Y124
L
A
P
K
L
P
S
Y
H
S
L
E
W
R
L
Frog
Xenopus laevis
NP_001085231
199
22908
Y124
L
E
P
D
L
S
H
Y
H
N
M
E
W
R
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650695
233
26312
L129
A
N
I
R
A
Y
R
L
V
N
L
D
W
R
L
Honey Bee
Apis mellifera
XP_001120781
202
23446
Y124
I
G
F
K
L
P
K
Y
H
D
M
E
W
R
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781013
199
22668
Y124
M
A
M
D
L
P
H
Y
R
N
L
E
W
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.9
95.4
N.A.
93.9
N.A.
N.A.
66.3
77.8
76.8
N.A.
N.A.
30.8
40
N.A.
60.3
Protein Similarity:
100
99.5
99.5
98.9
N.A.
98.4
N.A.
N.A.
71.3
84.9
86.4
N.A.
N.A.
51.5
63.8
N.A.
74.3
P-Site Identity:
100
100
100
80
N.A.
86.6
N.A.
N.A.
6.6
86.6
66.6
N.A.
N.A.
33.3
46.6
N.A.
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
33.3
93.3
73.3
N.A.
N.A.
40
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
55
0
0
10
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
28
0
0
0
0
0
19
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
0
82
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
19
0
73
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
19
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
64
0
0
0
91
0
0
10
10
0
73
0
10
0
82
% L
% Met:
10
0
10
0
0
0
0
0
0
0
19
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
55
0
0
0
0
0
% N
% Pro:
0
0
64
0
0
73
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
19
0
0
10
10
10
0
0
0
0
91
0
% R
% Ser:
10
10
0
28
0
10
55
0
0
28
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
91
0
0
% W
% Tyr:
0
10
0
0
0
10
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _