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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COMMD2 All Species: 31.52
Human Site: Y67 Identified Species: 69.33
UniProt: Q86X83 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X83 NP_057178.2 199 22745 Y67 H G V E G L T Y L L T E S S K
Chimpanzee Pan troglodytes XP_516817 199 22685 Y67 H G V E G L T Y L L T E S S K
Rhesus Macaque Macaca mulatta XP_001108551 199 22785 Y67 H G V E G L T Y L L T E S S K
Dog Lupus familis XP_542834 199 22751 Y67 H G V E G L T Y L L T E S S K
Cat Felis silvestris
Mouse Mus musculus Q8BXC6 199 22830 Y67 H G V E G L T Y L L T E S S K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516986 150 17315 S24 T Y L L T E S S K L M I S E L
Chicken Gallus gallus XP_422846 199 22283 Y67 H G V E G L M Y L L T E S S K
Frog Xenopus laevis NP_001085231 199 22908 Y67 Q A V E G L T Y L L C E S S K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650695 233 26312 I72 E A L I S L L I S V T T R V G
Honey Bee Apis mellifera XP_001120781 202 23446 N67 N S V E G L V N L L I E S C R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781013 199 22668 Y67 H G V E G L M Y L L T E S A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.9 95.4 N.A. 93.9 N.A. N.A. 66.3 77.8 76.8 N.A. N.A. 30.8 40 N.A. 60.3
Protein Similarity: 100 99.5 99.5 98.9 N.A. 98.4 N.A. N.A. 71.3 84.9 86.4 N.A. N.A. 51.5 63.8 N.A. 74.3
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 13.3 93.3 80 N.A. N.A. 13.3 53.3 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 26.6 93.3 80 N.A. N.A. 26.6 66.6 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 82 0 10 0 0 0 0 0 82 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 64 0 0 82 0 0 0 0 0 0 0 0 0 10 % G
% His: 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 10 0 0 10 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 64 % K
% Leu: 0 0 19 10 0 91 10 0 82 91 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 19 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 19 % R
% Ser: 0 10 0 0 10 0 10 10 10 0 0 0 91 64 0 % S
% Thr: 10 0 0 0 10 0 55 0 0 0 73 10 0 0 0 % T
% Val: 0 0 82 0 0 0 10 0 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 73 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _