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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIR1 All Species: 29.39
Human Site: S202 Identified Species: 58.79
UniProt: Q86X95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X95 NP_004873.3 450 52313 S202 P S Q E Y V A S E G E E D P E
Chimpanzee Pan troglodytes XP_001148591 450 52340 S202 P S Q E Y V A S E G E E D P E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535968 475 55209 S202 P S Q E Y V A S E G E E D P E
Cat Felis silvestris
Mouse Mus musculus Q9DA19 450 51819 S202 P S Q D Y V A S D C E E D P E
Rat Rattus norvegicus Q5U2T8 451 51398 S202 P S Q D Y V A S D G E E D P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514863 861 95412 S202 P S Q E Y V A S E D E E D P E
Chicken Gallus gallus Q5ZI03 460 53359 S200 P S Q E F V A S E G D D D P E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689017 177 20337
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649072 366 43629 D140 K W G H I N T D K E C T M Y S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_491654 560 65813 E233 Q L T R M K K E M T E E E M M
Sea Urchin Strong. purpuratus XP_794696 488 58217 S191 K N Q R F V G S S D D D E D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZ67 595 69129 K243 P N E E L R L K R D D P L T A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 84 N.A. 80.2 80.2 N.A. 43.5 70 N.A. 33.3 N.A. 38.4 N.A. 36.4 41.3
Protein Similarity: 100 99.5 N.A. 89.4 N.A. 86 86.6 N.A. 48.3 81.5 N.A. 36.6 N.A. 52.4 N.A. 51.2 56.5
P-Site Identity: 100 100 N.A. 100 N.A. 80 86.6 N.A. 93.3 80 N.A. 0 N.A. 0 N.A. 13.3 26.6
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 100 N.A. 93.3 100 N.A. 0 N.A. 6.6 N.A. 20 60
Percent
Protein Identity: N.A. N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 59 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % C
% Asp: 0 0 0 17 0 0 0 9 17 25 25 17 59 9 0 % D
% Glu: 0 0 9 50 0 0 0 9 42 9 59 59 17 0 67 % E
% Phe: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 9 0 0 42 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 17 0 0 0 0 9 9 9 9 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 9 0 9 0 0 0 0 0 9 0 0 % L
% Met: 0 0 0 0 9 0 0 0 9 0 0 0 9 9 9 % M
% Asn: 0 17 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 67 0 0 0 0 0 0 0 0 0 0 9 0 59 0 % P
% Gln: 9 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 17 0 9 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 59 0 0 0 0 0 67 9 0 0 0 0 0 9 % S
% Thr: 0 0 9 0 0 0 9 0 0 9 0 9 0 9 0 % T
% Val: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 50 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _