KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHFRL1
All Species:
52.73
Human Site:
S77
Identified Species:
89.23
UniProt:
Q86XF0
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XF0
NP_789785.1
187
21620
S77
D
R
I
N
L
V
L
S
R
E
L
K
E
P
P
Chimpanzee
Pan troglodytes
XP_001138276
186
21552
S77
D
R
I
N
L
V
L
S
R
E
L
K
E
P
P
Rhesus Macaque
Macaca mulatta
XP_001110551
187
21428
S77
G
R
I
N
L
V
L
S
R
E
L
K
E
P
P
Dog
Lupus familis
XP_851329
191
21936
S81
D
R
I
N
I
V
L
S
R
D
L
K
E
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P00375
187
21588
S77
D
R
I
N
I
V
L
S
R
E
L
K
E
P
P
Rat
Rattus norvegicus
Q920D2
187
21620
S77
D
R
I
N
I
V
L
S
R
E
L
K
E
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512236
463
51638
S88
D
R
I
N
I
V
L
S
R
E
L
K
E
P
P
Chicken
Gallus gallus
P00378
189
21631
S76
D
R
I
N
I
V
L
S
R
E
L
K
E
A
P
Frog
Xenopus laevis
NP_001088506
189
21877
S79
E
R
I
N
I
V
L
S
K
E
L
K
E
P
P
Zebra Danio
Brachydanio rerio
NP_571850
190
21680
S79
N
R
I
N
I
V
L
S
R
E
L
K
T
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17719
182
20756
S75
D
R
L
N
I
V
L
S
T
T
L
Q
E
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93341
189
21583
S75
G
R
L
N
I
V
L
S
R
Q
L
P
A
Q
K
Sea Urchin
Strong. purpuratus
XP_780421
189
21372
S80
D
R
V
N
V
V
L
S
N
S
L
T
E
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07807
211
24242
S80
N
R
M
N
V
I
I
S
R
S
F
K
D
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
92.5
84.8
N.A.
86.6
86.6
N.A.
29.5
68.2
59.2
57.8
N.A.
43.8
N.A.
34.3
50.2
Protein Similarity:
100
97.8
94.1
91
N.A.
93
93
N.A.
34.5
82.5
78.3
72.6
N.A.
62
N.A.
56
66.6
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
93.3
86.6
80
73.3
N.A.
53.3
N.A.
46.6
60
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
93.3
100
86.6
N.A.
73.3
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
65
0
0
0
0
0
0
0
0
8
0
0
8
8
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
65
0
0
79
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
72
0
65
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
79
0
0
8
% K
% Leu:
0
0
15
0
22
0
93
0
0
0
93
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
100
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
58
79
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% Q
% Arg:
0
100
0
0
0
0
0
0
79
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
15
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
8
0
8
8
0
0
% T
% Val:
0
0
8
0
15
93
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _