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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQCA1 All Species: 13.33
Human Site: S416 Identified Species: 32.59
UniProt: Q86XH1 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XH1 NP_079002.3 822 95341 S416 K D E S W N F S Q D Y D P E L
Chimpanzee Pan troglodytes XP_001152559 822 95341 S416 K D E S W N F S Q D Y D P E L
Rhesus Macaque Macaca mulatta XP_001083356 834 96786 S417 K D E S W N F S Q D F D P E L
Dog Lupus familis XP_534611 1092 123681 P673 R D E S W N F P Q D Y D P E L
Cat Felis silvestris
Mouse Mus musculus Q9CUL5 857 99856 P425 K D E S W N F P Q D Y D P E L
Rat Rattus norvegicus Q6AXQ7 822 95606 S416 R Y D N K H P S Q S F D S E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZK92 613 66247 S284 P A A N P A T S T H K A A P K
Frog Xenopus laevis Q6AZT2 600 65835 S271 Q A G A H T P S N R G A T G K
Zebra Danio Brachydanio rerio Q6NW58 570 63067 K241 T G P Q N N Q K G P T V K G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122486 823 95849 A405 K D E T M N A A Q L P Y L D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 94.2 63.1 N.A. 74 48.1 N.A. N.A. 21.8 21.4 21.1 N.A. N.A. 39.2 N.A. N.A.
Protein Similarity: 100 99.1 96.6 69.7 N.A. 84.8 68.7 N.A. N.A. 37.2 38.6 36.8 N.A. N.A. 62.2 N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 26.6 N.A. N.A. 6.6 6.6 6.6 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 60 N.A. N.A. 13.3 20 6.6 N.A. N.A. 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 10 10 0 10 10 10 0 0 0 20 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 60 10 0 0 0 0 0 0 50 0 60 0 10 0 % D
% Glu: 0 0 60 0 0 0 0 0 0 0 0 0 0 60 0 % E
% Phe: 0 0 0 0 0 0 50 0 0 0 20 0 0 0 0 % F
% Gly: 0 10 10 0 0 0 0 0 10 0 10 0 0 20 0 % G
% His: 0 0 0 0 10 10 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 50 0 0 0 10 0 0 10 0 0 10 0 10 0 30 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 50 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 10 70 0 0 10 0 0 0 0 0 0 % N
% Pro: 10 0 10 0 10 0 20 20 0 10 10 0 50 10 0 % P
% Gln: 10 0 0 10 0 0 10 0 70 0 0 0 0 0 0 % Q
% Arg: 20 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 50 0 0 0 60 0 10 0 0 10 0 0 % S
% Thr: 10 0 0 10 0 10 10 0 10 0 10 0 10 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 40 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _