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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO11
All Species:
14.24
Human Site:
S125
Identified Species:
26.11
UniProt:
Q86XK2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XK2
NP_036299.1
927
103585
S125
S
M
E
G
A
S
T
S
T
T
E
N
F
G
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113723
926
103438
S124
S
M
E
G
A
S
T
S
T
T
E
N
F
G
H
Dog
Lupus familis
XP_538484
686
76488
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPD1
843
94096
Q69
L
S
A
A
P
A
E
Q
Y
L
Q
E
K
L
P
Rat
Rattus norvegicus
Q7TSL3
843
94024
Q69
L
S
A
A
P
A
E
Q
Y
L
Q
E
K
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519223
689
76781
Chicken
Gallus gallus
XP_419357
1076
118785
S274
S
M
E
G
A
S
T
S
A
T
E
N
F
G
H
Frog
Xenopus laevis
NP_001086604
843
94076
Q69
L
P
M
A
P
A
E
Q
Y
L
Q
E
K
L
P
Zebra Danio
Brachydanio rerio
XP_696134
879
98123
S77
S
M
E
G
A
S
T
S
A
T
E
N
F
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649954
1182
124597
G337
Y
T
Q
G
G
E
M
G
P
S
A
G
A
T
G
Honey Bee
Apis mellifera
XP_395525
951
103332
G126
S
S
I
G
A
T
L
G
S
S
S
L
P
A
R
Nematode Worm
Caenorhab. elegans
NP_504661
936
105053
E131
R
D
F
S
I
E
D
E
S
G
T
N
L
E
A
Sea Urchin
Strong. purpuratus
XP_785605
875
96986
S75
D
L
S
S
S
P
G
S
S
P
M
T
R
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
72.8
N.A.
90.6
90.8
N.A.
69.2
81.7
89
92.7
N.A.
52.8
63.7
50.9
63.7
Protein Similarity:
100
N.A.
99.4
73.7
N.A.
90.8
90.9
N.A.
70.3
84.6
89.7
93.8
N.A.
62
75
66.2
75.8
P-Site Identity:
100
N.A.
100
0
N.A.
0
0
N.A.
0
93.3
0
93.3
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
N.A.
100
0
N.A.
13.3
13.3
N.A.
0
93.3
13.3
93.3
N.A.
20
40
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
24
39
24
0
0
16
0
8
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
31
0
0
16
24
8
0
0
31
24
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
31
0
0
% F
% Gly:
0
0
0
47
8
0
8
16
0
8
0
8
0
31
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
8
% K
% Leu:
24
8
0
0
0
0
8
0
0
24
0
8
8
24
0
% L
% Met:
0
31
8
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% N
% Pro:
0
8
0
0
24
8
0
0
8
8
0
0
8
0
24
% P
% Gln:
0
0
8
0
0
0
0
24
0
0
24
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
39
24
8
16
8
31
0
39
24
16
8
0
0
0
0
% S
% Thr:
0
8
0
0
0
8
31
0
16
31
8
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _