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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO11 All Species: 44.24
Human Site: Y646 Identified Species: 81.11
UniProt: Q86XK2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XK2 NP_036299.1 927 103585 Y646 K Q V G V Y F Y D N G H G V L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113723 926 103438 Y645 K Q V G V Y F Y D N G H G V L
Dog Lupus familis XP_538484 686 76488 R474 V Y I F G D G R G L I E G N D
Cat Felis silvestris
Mouse Mus musculus Q7TPD1 843 94096 Y562 K Q V G V Y F Y D N G H G V L
Rat Rattus norvegicus Q7TSL3 843 94024 Y562 K Q V G V Y F Y D N G H G V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519223 689 76781 N477 S D P T I R G N S I F N G N Q
Chicken Gallus gallus XP_419357 1076 118785 Y795 K Q V G V Y F Y D N G H G V L
Frog Xenopus laevis NP_001086604 843 94076 Y562 K Q V G V Y F Y D N G H G V L
Zebra Danio Brachydanio rerio XP_696134 879 98123 Y598 K Q V G V Y F Y D N G H G V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649954 1182 124597 Y901 K Q V G V Y F Y D N G H G K L
Honey Bee Apis mellifera XP_395525 951 103332 Y670 K Q V G V Y F Y D N G H G K L
Nematode Worm Caenorhab. elegans NP_504661 936 105053 Y656 K Q V G V Y F Y D Q G H G L L
Sea Urchin Strong. purpuratus XP_785605 875 96986 Y594 K Q V G V Y F Y D N G H G T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 72.8 N.A. 90.6 90.8 N.A. 69.2 81.7 89 92.7 N.A. 52.8 63.7 50.9 63.7
Protein Similarity: 100 N.A. 99.4 73.7 N.A. 90.8 90.9 N.A. 70.3 84.6 89.7 93.8 N.A. 62 75 66.2 75.8
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 6.6 100 100 100 N.A. 93.3 93.3 86.6 93.3
P-Site Similarity: 100 N.A. 100 13.3 N.A. 100 100 N.A. 20 100 100 100 N.A. 93.3 93.3 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 0 85 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 8 0 0 85 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 85 8 0 16 0 8 0 85 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 85 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 85 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 85 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 77 0 8 0 16 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 85 0 0 0 0 0 0 0 8 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 8 0 85 0 85 0 0 0 0 0 0 0 0 54 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 85 0 85 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _