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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKLE2
All Species:
9.7
Human Site:
Y445
Identified Species:
23.7
UniProt:
Q86XL3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XL3
NP_055929.1
938
104114
Y445
V
K
N
S
R
N
K
Y
D
K
T
P
E
D
V
Chimpanzee
Pan troglodytes
XP_001152324
477
52209
L19
A
A
L
A
W
E
L
L
G
A
S
V
L
L
I
Rhesus Macaque
Macaca mulatta
XP_001087028
488
53959
L30
G
H
Y
Y
V
P
L
L
R
A
E
D
T
S
S
Dog
Lupus familis
XP_852228
959
106035
Y450
V
K
N
P
R
N
K
Y
D
K
T
P
E
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1H6
964
106180
K452
I
V
K
N
R
K
N
K
Y
G
K
T
P
E
E
Rat
Rattus norvegicus
Q7TP65
931
103345
K453
I
V
K
N
P
R
N
K
Y
G
K
T
P
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510952
1025
112758
Y449
V
K
N
P
K
N
K
Y
E
K
T
P
E
D
V
Chicken
Gallus gallus
XP_415084
889
99899
T419
P
R
N
K
Y
D
Q
T
P
A
E
V
I
C
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001119867
961
106362
A458
G
P
L
S
P
S
K
A
D
E
F
R
R
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023515
580
64455
F122
L
V
D
S
N
P
R
F
L
V
N
T
G
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.1
49.1
73.9
N.A.
68.4
67.8
N.A.
58.2
54.6
N.A.
49.6
N.A.
N.A.
N.A.
23
N.A.
Protein Similarity:
100
49.6
50.4
82.4
N.A.
77.6
76.2
N.A.
69.7
66.8
N.A.
65.7
N.A.
N.A.
N.A.
34.8
N.A.
P-Site Identity:
100
0
0
93.3
N.A.
6.6
0
N.A.
80
6.6
N.A.
20
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
0
93.3
N.A.
26.6
20
N.A.
93.3
26.6
N.A.
33.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
0
0
10
0
30
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
0
10
0
0
30
0
0
10
0
30
20
% D
% Glu:
0
0
0
0
0
10
0
0
10
10
20
0
30
20
20
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
20
0
0
0
0
0
0
0
10
20
0
0
10
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
30
20
10
10
10
40
20
0
30
20
0
0
0
0
% K
% Leu:
10
0
20
0
0
0
20
20
10
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
40
20
10
30
20
0
0
0
10
0
0
0
0
% N
% Pro:
10
10
0
20
20
20
0
0
10
0
0
30
20
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
30
10
10
0
10
0
0
10
10
0
0
% R
% Ser:
0
0
0
30
0
10
0
0
0
0
10
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
30
30
10
0
0
% T
% Val:
30
30
0
0
10
0
0
0
0
10
0
20
0
0
30
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
10
10
10
0
0
30
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _