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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEX3D All Species: 10.3
Human Site: S67 Identified Species: 25.19
UniProt: Q86XN8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XN8 NP_976049.3 651 64883 S67 R L A L D Q L S A L G L G G A
Chimpanzee Pan troglodytes XP_524036 740 76557 G27 P S A P R E P G S A A K P S L
Rhesus Macaque Macaca mulatta XP_001096989 464 49865
Dog Lupus familis XP_855104 551 56066 P19 T D S A P Q A P L N G R L K G
Cat Felis silvestris
Mouse Mus musculus Q3UE17 643 65311 S58 R L A L D Q L S A L G L G G A
Rat Rattus norvegicus XP_234921 697 70530 S36 R L A L D Q L S A L G L G D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515618 613 64857 S31 R C V H R K C S G R G V S T Y
Chicken Gallus gallus XP_418202 443 47323
Frog Xenopus laevis A1L3F4 507 54145
Zebra Danio Brachydanio rerio NP_001074462 537 57239 D19 S G S G G Q G D A L D D Q R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.6 42.4 63.9 N.A. 77.5 68 N.A. 52.3 49.7 43.6 43.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 78.5 50 67.9 N.A. 81.8 73.1 N.A. 61.7 56.3 53 52.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 0 13.3 N.A. 100 93.3 N.A. 20 0 0 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 0 20 N.A. 100 93.3 N.A. 33.3 0 0 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 40 10 0 0 10 0 40 10 10 0 0 0 40 % A
% Cys: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 30 0 0 10 0 0 10 10 0 10 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 10 0 10 10 10 0 50 0 30 20 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 10 0 10 0 % K
% Leu: 0 30 0 30 0 0 30 0 10 40 0 30 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 0 10 10 0 10 10 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 50 0 0 0 0 0 0 10 0 0 % Q
% Arg: 40 0 0 0 20 0 0 0 0 10 0 10 0 10 0 % R
% Ser: 10 10 20 0 0 0 0 40 10 0 0 0 10 10 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _