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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEX3D
All Species:
21.52
Human Site:
T641
Identified Species:
52.59
UniProt:
Q86XN8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XN8
NP_976049.3
651
64883
T641
P
E
C
P
A
C
R
T
P
A
T
Q
A
I
H
Chimpanzee
Pan troglodytes
XP_524036
740
76557
T715
P
E
C
P
A
C
R
T
P
A
T
Q
A
I
R
Rhesus Macaque
Macaca mulatta
XP_001096989
464
49865
A455
S
C
P
V
C
Q
T
A
V
T
Q
A
I
Q
I
Dog
Lupus familis
XP_855104
551
56066
T541
P
E
C
P
A
C
R
T
P
A
T
Q
A
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3UE17
643
65311
T633
P
E
C
P
A
C
R
T
P
A
T
Q
A
I
H
Rat
Rattus norvegicus
XP_234921
697
70530
T687
P
E
C
P
A
C
R
T
P
A
T
Q
A
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515618
613
64857
T603
P
E
C
P
V
C
H
T
P
V
T
Q
A
I
H
Chicken
Gallus gallus
XP_418202
443
47323
P434
E
C
P
A
C
H
T
P
A
T
Q
A
I
H
I
Frog
Xenopus laevis
A1L3F4
507
54145
A497
P
Q
C
P
V
C
H
A
G
V
T
Q
A
I
R
Zebra Danio
Brachydanio rerio
NP_001074462
537
57239
A527
P
K
C
P
V
C
H
A
A
V
T
Q
A
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.6
42.4
63.9
N.A.
77.5
68
N.A.
52.3
49.7
43.6
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
78.5
50
67.9
N.A.
81.8
73.1
N.A.
61.7
56.3
53
52.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
100
N.A.
100
100
N.A.
80
0
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
0
100
N.A.
100
100
N.A.
80
0
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
50
0
0
30
20
50
0
20
80
0
0
% A
% Cys:
0
20
80
0
20
80
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
30
0
0
0
0
0
0
10
50
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
20
80
20
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
80
0
20
80
0
0
0
10
60
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
0
0
0
0
20
80
0
10
0
% Q
% Arg:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
30
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
20
60
0
20
80
0
0
0
0
% T
% Val:
0
0
0
10
30
0
0
0
10
30
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _