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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKH
All Species:
18.18
Human Site:
Y488
Identified Species:
50
UniProt:
Q86XP1
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XP1
NP_690874.2
1220
134866
Y488
E
E
F
Y
M
T
I
Y
E
D
S
V
A
T
H
Chimpanzee
Pan troglodytes
XP_001151474
1220
134870
Y488
E
E
F
Y
M
T
I
Y
E
D
S
V
A
T
H
Rhesus Macaque
Macaca mulatta
XP_001114920
1167
129871
Y436
E
V
Q
Q
I
L
F
Y
E
D
S
V
A
A
H
Dog
Lupus familis
XP_534133
1182
132580
Y450
E
E
F
Y
M
T
I
Y
E
D
S
V
A
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507672
1254
138458
Y519
E
E
C
Q
M
S
S
Y
E
D
S
V
A
A
H
Chicken
Gallus gallus
XP_001232791
1333
149344
Y596
E
E
C
Q
I
S
A
Y
E
D
S
V
A
A
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108193
586
65385
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JQ65
1895
211641
V509
E
A
M
L
T
G
M
V
T
S
A
N
H
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202627
1158
127377
N418
Q
I
M
K
E
K
C
N
L
L
N
E
K
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
62.2
90.7
N.A.
N.A.
N.A.
N.A.
82.3
76.8
N.A.
39
N.A.
34.9
N.A.
N.A.
51.5
Protein Similarity:
100
99.8
73.4
92.8
N.A.
N.A.
N.A.
N.A.
88.1
82.9
N.A.
43.2
N.A.
46.5
N.A.
N.A.
64.1
P-Site Identity:
100
100
53.3
93.3
N.A.
N.A.
N.A.
N.A.
66.6
60
N.A.
0
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
60
93.3
N.A.
N.A.
N.A.
N.A.
73.3
73.3
N.A.
0
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
12
0
0
0
12
0
67
45
0
% A
% Cys:
0
0
23
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% D
% Glu:
78
56
0
0
12
0
0
0
67
0
0
12
0
0
0
% E
% Phe:
0
0
34
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
67
% H
% Ile:
0
12
0
0
23
0
34
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
12
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
0
0
12
0
12
0
0
12
12
0
0
0
12
12
% L
% Met:
0
0
23
0
45
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
12
12
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
12
34
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
23
12
0
0
12
67
0
0
0
0
% S
% Thr:
0
0
0
0
12
34
0
0
12
0
0
0
0
23
0
% T
% Val:
0
12
0
0
0
0
0
12
0
0
0
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
34
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _