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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX42
All Species:
22.73
Human Site:
S423
Identified Species:
41.67
UniProt:
Q86XP3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XP3
NP_031398.2
938
102975
S423
G
F
E
Y
Q
V
R
S
I
A
S
H
V
R
P
Chimpanzee
Pan troglodytes
XP_001147663
938
102943
S423
G
F
E
Y
Q
V
R
S
I
A
S
H
V
R
P
Rhesus Macaque
Macaca mulatta
XP_001116381
937
102784
S423
G
F
E
Y
Q
V
R
S
I
A
S
H
V
R
P
Dog
Lupus familis
XP_537598
696
77647
I224
F
Y
N
E
H
E
E
I
T
N
L
T
P
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q810A7
929
101946
S423
G
F
E
Y
Q
V
R
S
I
A
S
H
V
R
P
Rat
Rattus norvegicus
Q62780
1032
117367
R545
G
F
E
P
Q
V
M
R
I
V
D
N
V
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F485
944
103035
S423
G
F
E
Y
Q
V
R
S
I
A
S
H
V
R
P
Frog
Xenopus laevis
Q7ZY47
947
104061
S420
G
F
E
Y
Q
V
R
S
I
A
N
H
V
R
P
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
R513
G
F
E
P
Q
V
M
R
I
V
D
N
V
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648413
791
87235
K319
I
A
K
T
G
S
G
K
T
A
A
F
I
W
P
Honey Bee
Apis mellifera
XP_624210
772
85916
K300
R
D
I
I
G
I
A
K
T
G
S
G
K
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22907
760
83032
V288
A
F
V
L
P
M
I
V
H
I
M
D
Q
P
E
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
E74
L
P
K
L
P
T
F
E
K
N
F
Y
V
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
72.9
N.A.
95.5
30
N.A.
N.A.
83.5
75.1
27.8
N.A.
46.3
48.8
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
73.6
N.A.
97
46.7
N.A.
N.A.
88.9
83.6
46.1
N.A.
59.7
61.5
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
60
N.A.
N.A.
100
93.3
60
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
66.6
N.A.
N.A.
100
100
66.6
N.A.
33.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.3
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
0
54
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
16
8
0
0
0
% D
% Glu:
0
0
62
8
0
8
8
8
0
0
0
0
0
8
8
% E
% Phe:
8
70
0
0
0
0
8
0
0
0
8
8
0
0
0
% F
% Gly:
62
0
0
0
16
0
8
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
47
0
0
8
% H
% Ile:
8
0
8
8
0
8
8
8
62
8
0
0
8
0
0
% I
% Lys:
0
0
16
0
0
0
0
16
8
0
0
0
8
0
0
% K
% Leu:
8
0
0
16
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
16
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
16
8
16
0
0
0
% N
% Pro:
0
8
0
16
16
0
0
0
0
0
0
0
8
8
70
% P
% Gln:
0
0
0
0
62
0
0
0
0
0
0
0
8
8
8
% Q
% Arg:
8
0
0
0
0
0
47
16
0
0
0
0
0
62
0
% R
% Ser:
0
0
0
0
0
8
0
47
0
0
47
0
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
0
24
0
0
8
0
8
0
% T
% Val:
0
0
8
0
0
62
0
8
0
16
0
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
47
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _