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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX42
All Species:
8.79
Human Site:
S758
Identified Species:
16.11
UniProt:
Q86XP3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XP3
NP_031398.2
938
102975
S758
S
P
D
S
P
V
T
S
A
A
K
G
I
P
G
Chimpanzee
Pan troglodytes
XP_001147663
938
102943
S758
S
P
D
S
P
V
T
S
A
T
K
G
I
P
G
Rhesus Macaque
Macaca mulatta
XP_001116381
937
102784
S758
S
P
D
S
P
V
A
S
A
T
K
G
I
P
G
Dog
Lupus familis
XP_537598
696
77647
Q520
E
L
A
N
N
L
K
Q
E
G
H
N
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q810A7
929
101946
P753
A
Q
Q
G
H
N
S
P
D
N
P
M
T
S
S
Rat
Rattus norvegicus
Q62780
1032
117367
G844
S
A
P
A
P
T
A
G
N
A
E
K
L
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F485
944
103035
A759
N
P
D
S
P
I
A
A
T
A
A
A
K
G
V
Frog
Xenopus laevis
Q7ZY47
947
104061
P756
P
A
E
A
A
P
P
P
V
H
T
A
M
L
G
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
A839
N
I
Q
K
L
E
I
A
K
K
L
A
L
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648413
791
87235
Y615
A
G
E
K
G
N
A
Y
T
L
V
T
D
K
D
Honey Bee
Apis mellifera
XP_624210
772
85916
G596
I
G
R
T
G
R
A
G
E
K
G
T
A
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22907
760
83032
R584
L
V
T
Q
R
E
A
R
F
A
G
E
L
V
N
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
K370
T
L
I
F
A
S
T
K
R
M
C
D
D
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
72.9
N.A.
95.5
30
N.A.
N.A.
83.5
75.1
27.8
N.A.
46.3
48.8
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
73.6
N.A.
97
46.7
N.A.
N.A.
88.9
83.6
46.1
N.A.
59.7
61.5
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
0
N.A.
0
20
N.A.
N.A.
33.3
6.6
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
20
N.A.
13.3
40
N.A.
N.A.
53.3
26.6
20
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.3
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
8
16
16
0
47
16
24
31
8
24
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
31
0
0
0
0
0
8
0
0
8
16
0
8
% D
% Glu:
8
0
16
0
0
16
0
0
16
0
8
8
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
16
0
8
16
0
0
16
0
8
16
24
0
16
31
% G
% His:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
8
8
8
0
0
8
8
0
0
0
0
0
24
8
16
% I
% Lys:
0
0
0
16
0
0
8
8
8
16
24
8
8
8
0
% K
% Leu:
8
16
0
0
8
8
0
0
0
8
8
0
31
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% M
% Asn:
16
0
0
8
8
16
0
0
8
8
0
8
0
0
8
% N
% Pro:
8
31
8
0
39
8
8
16
0
0
8
0
0
24
0
% P
% Gln:
0
8
16
8
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
8
0
8
8
0
0
0
0
8
0
% R
% Ser:
31
0
0
31
0
8
8
24
0
0
0
0
0
8
8
% S
% Thr:
8
0
8
8
0
8
24
0
16
16
8
16
8
0
16
% T
% Val:
0
8
0
0
0
24
0
0
8
0
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _