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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEP57 All Species: 11.82
Human Site: S343 Identified Species: 26
UniProt: Q86XR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XR8 NP_055494.2 500 57089 S343 V S S R G G K S K K L S V T P
Chimpanzee Pan troglodytes XP_001145217 500 56971 S343 V S S R G G K S K K L S V T P
Rhesus Macaque Macaca mulatta XP_001093565 499 56751 K342 Q V S L R G G K S K K L S V T
Dog Lupus familis XP_533972 501 57208 S343 S S S R S G K S K K L S G T P
Cat Felis silvestris
Mouse Mus musculus Q8CEE0 500 56891 S342 K Q A C S R V S K S K K S V V
Rat Rattus norvegicus B4F7A7 499 57022 S342 K Q A C S R G S K S K K S V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511190 512 58704 R353 T G A T R C S R V Q R P P V S
Chicken Gallus gallus XP_417188 497 56836 R338 S A G R P G S R S R K P P L P
Frog Xenopus laevis Q5FWP9 488 55089 G331 K P S I L P G G S R S I P T R
Zebra Danio Brachydanio rerio NP_001074152 440 49270 S310 G G G C T S A S S S S T S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790540 519 58520 S361 A K V R R S T S V S S S A G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97 90.4 N.A. 87.8 86 N.A. 64 60.7 36.2 40.5 N.A. N.A. N.A. N.A. 36.6
Protein Similarity: 100 99.8 97.5 94.2 N.A. 91.8 91.4 N.A. 77.3 74.5 57.2 57.5 N.A. N.A. N.A. N.A. 58
P-Site Identity: 100 100 20 80 N.A. 13.3 13.3 N.A. 0 20 13.3 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 20 80 N.A. 20 20 N.A. 13.3 33.3 20 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 28 0 0 0 10 0 0 0 0 0 10 0 10 % A
% Cys: 0 0 0 28 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 19 19 0 19 46 28 10 0 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 28 10 0 0 0 0 28 10 46 37 37 19 0 0 0 % K
% Leu: 0 0 0 10 10 0 0 0 0 0 28 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 10 10 0 0 0 0 0 19 28 0 37 % P
% Gln: 10 19 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 46 28 19 0 19 0 19 10 0 0 0 10 % R
% Ser: 19 28 46 0 28 19 19 64 37 37 28 37 37 10 28 % S
% Thr: 10 0 0 10 10 0 10 0 0 0 0 10 0 37 10 % T
% Val: 19 10 10 0 0 0 10 0 19 0 0 0 19 37 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _