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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEP57 All Species: 22.12
Human Site: S353 Identified Species: 48.67
UniProt: Q86XR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XR8 NP_055494.2 500 57089 S353 L S V T P P S S N G I N E E L
Chimpanzee Pan troglodytes XP_001145217 500 56971 S353 L S V T P P S S N G I N E E L
Rhesus Macaque Macaca mulatta XP_001093565 499 56751 S352 K L S V T S P S N G I N E E L
Dog Lupus familis XP_533972 501 57208 S353 L S G T P P S S N S V N E E L
Cat Felis silvestris
Mouse Mus musculus Q8CEE0 500 56891 S352 K K S V V P P S S S V N E E L
Rat Rattus norvegicus B4F7A7 499 57022 S352 K K S V A P P S S S V N E E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511190 512 58704 S363 R P P V S T A S S A S H E E L
Chicken Gallus gallus XP_417188 497 56836 Y348 K P P L P K D Y S S S Q E E L
Frog Xenopus laevis Q5FWP9 488 55089 S341 S I P T R L M S S S T G D T L
Zebra Danio Brachydanio rerio NP_001074152 440 49270 C320 S T S S S C S C S E D L S E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790540 519 58520 S371 S S A G S D L S D L V L G L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97 90.4 N.A. 87.8 86 N.A. 64 60.7 36.2 40.5 N.A. N.A. N.A. N.A. 36.6
Protein Similarity: 100 99.8 97.5 94.2 N.A. 91.8 91.4 N.A. 77.3 74.5 57.2 57.5 N.A. N.A. N.A. N.A. 58
P-Site Identity: 100 100 53.3 80 N.A. 40 40 N.A. 26.6 26.6 20 20 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 53.3 86.6 N.A. 53.3 53.3 N.A. 46.6 33.3 33.3 40 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 10 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 10 0 10 0 10 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 73 82 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 0 0 0 0 28 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 28 0 0 0 0 % I
% Lys: 37 19 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 28 10 0 10 0 10 10 0 0 10 0 19 0 10 91 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 37 0 0 55 0 0 0 % N
% Pro: 0 19 28 0 37 46 28 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % Q
% Arg: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 37 37 10 28 10 37 82 55 46 19 0 10 0 0 % S
% Thr: 0 10 0 37 10 10 0 0 0 0 10 0 0 10 0 % T
% Val: 0 0 19 37 10 0 0 0 0 0 37 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _