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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CEP57
All Species:
16.97
Human Site:
T250
Identified Species:
37.33
UniProt:
Q86XR8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XR8
NP_055494.2
500
57089
T250
L
I
F
E
D
K
A
T
P
C
V
P
N
A
R
Chimpanzee
Pan troglodytes
XP_001145217
500
56971
T250
L
I
F
E
D
K
A
T
P
C
V
P
N
A
R
Rhesus Macaque
Macaca mulatta
XP_001093565
499
56751
T250
L
T
F
E
D
K
A
T
P
R
V
P
S
A
R
Dog
Lupus familis
XP_533972
501
57208
T250
I
I
F
E
D
K
T
T
P
Y
V
P
S
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEE0
500
56891
S251
I
F
E
D
K
T
T
S
C
V
S
T
S
T
R
Rat
Rattus norvegicus
B4F7A7
499
57022
S251
I
F
E
D
R
N
T
S
C
V
S
T
S
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511190
512
58704
A257
R
I
L
F
E
E
K
A
A
A
S
K
P
R
R
Chicken
Gallus gallus
XP_417188
497
56836
P244
L
L
I
Q
A
A
S
P
L
L
S
P
K
A
R
Frog
Xenopus laevis
Q5FWP9
488
55089
S235
I
L
L
S
S
A
S
S
Q
N
S
T
Q
R
K
Zebra Danio
Brachydanio rerio
NP_001074152
440
49270
L220
A
A
Q
L
Q
T
G
L
E
A
N
R
L
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790540
519
58520
L268
L
A
E
T
N
R
I
L
L
A
T
E
E
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97
90.4
N.A.
87.8
86
N.A.
64
60.7
36.2
40.5
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
99.8
97.5
94.2
N.A.
91.8
91.4
N.A.
77.3
74.5
57.2
57.5
N.A.
N.A.
N.A.
N.A.
58
P-Site Identity:
100
100
80
73.3
N.A.
6.6
6.6
N.A.
13.3
26.6
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
86.6
N.A.
33.3
33.3
N.A.
26.6
46.6
33.3
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
0
10
19
28
10
10
28
0
0
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
19
19
0
0
0
0
0
% C
% Asp:
0
0
0
19
37
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
28
37
10
10
0
0
10
0
0
10
10
0
0
% E
% Phe:
0
19
37
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
37
10
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
37
10
0
0
0
0
10
10
0
10
% K
% Leu:
46
19
19
10
0
0
0
19
19
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
10
10
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
37
0
0
46
10
0
0
% P
% Gln:
0
0
10
10
10
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
10
10
0
0
0
10
0
10
0
19
73
% R
% Ser:
0
0
0
10
10
0
19
28
0
0
46
0
37
0
0
% S
% Thr:
0
10
0
10
0
19
28
37
0
0
10
28
0
19
10
% T
% Val:
0
0
0
0
0
0
0
0
0
19
37
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _