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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CEP57
All Species:
22.73
Human Site:
Y421
Identified Species:
50
UniProt:
Q86XR8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XR8
NP_055494.2
500
57089
Y421
Q
I
T
K
V
R
K
Y
Q
A
Q
L
E
K
Q
Chimpanzee
Pan troglodytes
XP_001145217
500
56971
Y421
Q
I
T
K
V
R
K
Y
Q
A
Q
L
E
K
Q
Rhesus Macaque
Macaca mulatta
XP_001093565
499
56751
Y420
Q
I
T
K
V
R
K
Y
Q
A
Q
L
E
K
Q
Dog
Lupus familis
XP_533972
501
57208
Y421
Q
I
T
K
V
R
K
Y
Q
A
Q
L
E
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEE0
500
56891
Y420
Q
I
T
K
V
R
K
Y
Q
A
Q
L
E
K
Q
Rat
Rattus norvegicus
B4F7A7
499
57022
Y420
Q
I
T
K
V
R
K
Y
Q
A
Q
L
E
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511190
512
58704
H431
Q
I
M
K
V
R
K
H
Q
S
W
I
Q
V
N
Chicken
Gallus gallus
XP_417188
497
56836
H416
Q
I
S
K
V
R
R
H
W
L
Q
L
E
R
L
Frog
Xenopus laevis
Q5FWP9
488
55089
H409
Q
I
I
K
L
K
R
H
Q
L
N
V
A
K
L
Zebra Danio
Brachydanio rerio
NP_001074152
440
49270
Q377
R
M
E
N
K
A
E
Q
I
S
K
L
R
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790540
519
58520
H431
Q
I
A
K
L
K
K
H
K
E
Q
L
S
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97
90.4
N.A.
87.8
86
N.A.
64
60.7
36.2
40.5
N.A.
N.A.
N.A.
N.A.
36.6
Protein Similarity:
100
99.8
97.5
94.2
N.A.
91.8
91.4
N.A.
77.3
74.5
57.2
57.5
N.A.
N.A.
N.A.
N.A.
58
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
46.6
53.3
33.3
6.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
73.3
80
66.6
46.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
55
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
0
0
10
0
0
64
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% H
% Ile:
0
91
10
0
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
0
91
10
19
73
0
10
0
10
0
0
64
10
% K
% Leu:
0
0
0
0
19
0
0
0
0
19
0
82
0
0
19
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
91
0
0
0
0
0
0
10
73
0
73
0
10
0
55
% Q
% Arg:
10
0
0
0
0
73
19
0
0
0
0
0
10
19
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
19
0
0
10
0
0
% S
% Thr:
0
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
73
0
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _