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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGPTL5
All Species:
17.27
Human Site:
T253
Identified Species:
47.5
UniProt:
Q86XS5
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XS5
NP_835228.2
388
44144
T253
A
L
E
S
E
D
D
T
L
A
Y
A
S
Y
D
Chimpanzee
Pan troglodytes
XP_522161
388
44186
T253
A
L
E
S
E
D
D
T
L
A
Y
A
S
Y
D
Rhesus Macaque
Macaca mulatta
XP_001095748
388
44341
T253
S
L
E
S
E
D
D
T
L
A
Y
A
S
Y
D
Dog
Lupus familis
XP_854721
489
55149
T354
A
L
E
S
E
D
D
T
F
A
Y
A
S
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5M8C6
314
36458
F193
R
F
A
Q
Y
E
K
F
K
V
G
D
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510310
389
44136
M254
A
L
E
S
E
D
D
M
S
A
S
A
S
Y
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XK91
457
51018
F334
L
R
I
D
L
E
D
F
D
N
A
T
A
Y
A
Zebra Danio
Brachydanio rerio
XP_002666042
406
46185
S271
S
L
I
S
Q
D
E
S
T
A
Y
A
S
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785428
223
25076
L102
D
Y
E
L
R
I
D
L
Q
D
Y
N
G
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.4
70.5
N.A.
N.A.
29.3
N.A.
77.6
N.A.
24.2
47.5
N.A.
N.A.
N.A.
N.A.
24.2
Protein Similarity:
100
99.2
98.4
75.2
N.A.
N.A.
44
N.A.
85.5
N.A.
40.4
67.7
N.A.
N.A.
N.A.
N.A.
36.3
P-Site Identity:
100
100
93.3
93.3
N.A.
N.A.
0
N.A.
80
N.A.
13.3
60
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
N.A.
6.6
N.A.
80
N.A.
26.6
86.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
12
0
0
0
0
0
0
67
12
67
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
12
0
67
78
0
12
12
0
12
0
0
67
% D
% Glu:
0
0
67
0
56
23
12
0
0
0
0
0
12
0
0
% E
% Phe:
0
12
0
0
0
0
0
23
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
0
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
0
12
0
0
0
0
12
12
% K
% Leu:
12
67
0
12
12
0
0
12
34
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
12
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
12
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
23
0
0
67
0
0
0
12
12
0
12
0
67
0
12
% S
% Thr:
0
0
0
0
0
0
0
45
12
0
0
12
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
0
0
0
0
67
0
0
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _