KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGPTL5
All Species:
20
Human Site:
Y177
Identified Species:
55
UniProt:
Q86XS5
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XS5
NP_835228.2
388
44144
Y177
I
H
P
E
G
S
S
Y
P
F
E
V
M
C
D
Chimpanzee
Pan troglodytes
XP_522161
388
44186
Y177
I
H
P
E
G
S
S
Y
P
F
E
V
M
C
D
Rhesus Macaque
Macaca mulatta
XP_001095748
388
44341
Y177
I
H
P
E
G
S
S
Y
P
F
E
V
M
C
D
Dog
Lupus familis
XP_854721
489
55149
Y278
I
Y
P
E
G
S
S
Y
P
F
E
V
M
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5M8C6
314
36458
Q126
G
G
G
W
T
V
I
Q
R
R
S
D
G
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510310
389
44136
Y178
I
H
P
E
G
A
G
Y
P
F
E
V
M
C
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XK91
457
51018
S263
V
F
P
I
H
Y
P
S
G
F
Q
V
F
C
D
Zebra Danio
Brachydanio rerio
XP_002666042
406
46185
D187
I
I
Q
P
E
N
T
D
V
S
F
E
E
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785428
223
25076
P35
L
P
D
G
C
G
Q
P
F
Q
V
F
C
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.4
70.5
N.A.
N.A.
29.3
N.A.
77.6
N.A.
24.2
47.5
N.A.
N.A.
N.A.
N.A.
24.2
Protein Similarity:
100
99.2
98.4
75.2
N.A.
N.A.
44
N.A.
85.5
N.A.
40.4
67.7
N.A.
N.A.
N.A.
N.A.
36.3
P-Site Identity:
100
100
100
93.3
N.A.
N.A.
0
N.A.
86.6
N.A.
33.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
N.A.
6.6
N.A.
93.3
N.A.
46.6
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
12
67
0
% C
% Asp:
0
0
12
0
0
0
0
12
0
0
0
12
0
12
67
% D
% Glu:
0
0
0
56
12
0
0
0
0
0
56
12
12
0
12
% E
% Phe:
0
12
0
0
0
0
0
0
12
67
12
12
12
0
0
% F
% Gly:
12
12
12
12
56
12
12
0
12
0
0
0
12
0
0
% G
% His:
0
45
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
12
0
12
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
56
0
12
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
67
12
0
0
12
12
56
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
12
12
0
12
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
45
45
12
0
12
12
0
0
23
0
% S
% Thr:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
12
% T
% Val:
12
0
0
0
0
12
0
0
12
0
12
67
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
12
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _