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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS37D All Species: 17.88
Human Site: S213 Identified Species: 43.7
UniProt: Q86XT2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XT2 NP_001071089.1 251 27730 S213 G P P A V P R S L P P L D S R
Chimpanzee Pan troglodytes XP_527783 219 24105 S181 G P P A V P R S L P P L D S R
Rhesus Macaque Macaca mulatta XP_001115161 285 31622 S247 G P P A V P R S L P P L D S R
Dog Lupus familis XP_546924 388 41836 S350 G P P A V P R S L P P L D S R
Cat Felis silvestris
Mouse Mus musculus Q810I0 261 28544 S223 P P P A V P R S L P P L D S R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514899 391 42738 P198 P P P P S A A P P F P L P Y S
Chicken Gallus gallus XP_420953 356 38743 P267 S T P G Y P K P P P G A S S A
Frog Xenopus laevis NP_001083414 287 32077 R202 S P P P V T P R R P V P P P P
Zebra Danio Brachydanio rerio NP_001071253 323 35175 Q232 T N P S T A F Q P Y P S Q G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120612 218 24547 P180 S H S V T S G P G Y P I A S N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84 77.1 63.1 N.A. 92.3 N.A. N.A. 21.2 23.8 33.7 21.9 N.A. N.A. 27.8 N.A. N.A.
Protein Similarity: 100 85.6 78.5 64.1 N.A. 94.2 N.A. N.A. 31.4 35.6 48.7 38.3 N.A. N.A. 48.6 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 26.6 26.6 26.6 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 26.6 33.3 26.6 20 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 50 0 20 10 0 0 0 0 10 10 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % F
% Gly: 40 0 0 10 0 0 10 0 10 0 10 0 0 10 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 50 0 0 60 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 20 70 90 20 0 60 10 30 30 70 80 10 20 10 10 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 50 10 10 0 0 0 0 0 50 % R
% Ser: 30 0 10 10 10 10 0 50 0 0 0 10 10 70 10 % S
% Thr: 10 10 0 0 20 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 60 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 20 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _