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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM50
All Species:
20
Human Site:
S335
Identified Species:
55
UniProt:
Q86XT4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XT4
NP_835226.1
487
54774
S335
Q
P
E
R
F
D
Y
S
T
C
V
L
A
S
R
Chimpanzee
Pan troglodytes
Q1XHU0
518
59727
P322
E
K
N
F
S
N
F
P
R
Q
Y
F
A
L
R
Rhesus Macaque
Macaca mulatta
Q0PF16
497
57280
C349
S
L
T
N
F
N
Y
C
T
G
V
L
G
S
Q
Dog
Lupus familis
XP_546929
487
55202
S335
Q
P
E
R
F
D
Y
S
T
C
V
L
A
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q810I2
483
54589
S334
Q
P
E
R
F
D
Y
S
T
C
V
L
A
S
K
Rat
Rattus norvegicus
Q810I1
483
54701
S334
Q
P
E
R
F
D
Y
S
T
C
V
L
A
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509541
527
60558
C334
I
E
L
K
K
D
T
C
S
F
P
L
Q
H
F
Chicken
Gallus gallus
XP_415709
492
55730
S336
N
P
K
R
F
D
S
S
N
C
I
L
T
C
K
Frog
Xenopus laevis
Q6PGR9
477
54096
S332
E
P
N
R
F
D
K
S
N
C
L
V
S
K
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
25.5
89.1
N.A.
87.2
86.6
N.A.
29.6
60.7
33
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.6
44.6
94.4
N.A.
92.1
91.9
N.A.
46.2
77.8
55.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
40
86.6
N.A.
93.3
93.3
N.A.
13.3
46.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
53.3
100
N.A.
100
100
N.A.
26.6
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
56
0
0
% A
% Cys:
0
0
0
0
0
0
0
23
0
67
0
0
0
12
0
% C
% Asp:
0
0
0
0
0
78
0
0
0
0
0
0
0
0
0
% D
% Glu:
23
12
45
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
78
0
12
0
0
12
0
12
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
12
12
12
12
0
12
0
0
0
0
0
0
12
34
% K
% Leu:
0
12
12
0
0
0
0
0
0
0
12
78
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
23
12
0
23
0
0
23
0
0
0
0
12
0
% N
% Pro:
0
67
0
0
0
0
0
12
0
0
12
0
0
0
0
% P
% Gln:
45
0
0
0
0
0
0
0
0
12
0
0
12
0
34
% Q
% Arg:
0
0
0
67
0
0
0
0
12
0
0
0
0
0
23
% R
% Ser:
12
0
0
0
12
0
12
67
12
0
0
0
12
45
0
% S
% Thr:
0
0
12
0
0
0
12
0
56
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
56
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
56
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _