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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM50 All Species: 10.61
Human Site: T426 Identified Species: 29.17
UniProt: Q86XT4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XT4 NP_835226.1 487 54774 T426 H Y E Q G E L T F F D A D R P
Chimpanzee Pan troglodytes Q1XHU0 518 59727 K456 L H I K V K P K R V G I F L D
Rhesus Macaque Macaca mulatta Q0PF16 497 57280 I437 I V P L S V I I C P D R V G V
Dog Lupus familis XP_546929 487 55202 T426 H Y E Q G E L T F F D A D R P
Cat Felis silvestris
Mouse Mus musculus Q810I2 483 54589 E423 Y L H Y E Q G E L T F F D A D
Rat Rattus norvegicus Q810I1 483 54701 E420 I G V Y L H Y E Q G E L T F F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509541 527 60558 T461 A A L T S N P T P L L L R V K
Chicken Gallus gallus XP_415709 492 55730 T427 H Y E K G E L T F Y N A D S P
Frog Xenopus laevis Q6PGR9 477 54096 Y416 R P E K I G V Y L S F S D G V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.4 25.5 89.1 N.A. 87.2 86.6 N.A. 29.6 60.7 33 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 47.6 44.6 94.4 N.A. 92.1 91.9 N.A. 46.2 77.8 55.2 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 100 N.A. 6.6 0 N.A. 6.6 73.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 13.3 100 N.A. 20 6.6 N.A. 6.6 93.3 33.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 0 0 0 0 0 0 0 0 34 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 34 0 56 0 23 % D
% Glu: 0 0 45 0 12 34 0 23 0 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 23 23 12 12 12 12 % F
% Gly: 0 12 0 0 34 12 12 0 0 12 12 0 0 23 0 % G
% His: 34 12 12 0 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 23 0 12 0 12 0 12 12 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 34 0 12 0 12 0 0 0 0 0 0 12 % K
% Leu: 12 12 12 12 12 0 34 0 23 12 12 23 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 0 0 0 12 0 0 0 0 % N
% Pro: 0 12 12 0 0 0 23 0 12 12 0 0 0 0 34 % P
% Gln: 0 0 0 23 0 12 0 0 12 0 0 0 0 0 0 % Q
% Arg: 12 0 0 0 0 0 0 0 12 0 0 12 12 23 0 % R
% Ser: 0 0 0 0 23 0 0 0 0 12 0 12 0 12 0 % S
% Thr: 0 0 0 12 0 0 0 45 0 12 0 0 12 0 0 % T
% Val: 0 12 12 0 12 12 12 0 0 12 0 0 12 12 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 34 0 23 0 0 12 12 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _