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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM50
All Species:
11.52
Human Site:
Y451
Identified Species:
31.67
UniProt:
Q86XT4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XT4
NP_835226.1
487
54774
Y451
A
D
F
Q
G
K
L
Y
P
I
L
D
T
C
W
Chimpanzee
Pan troglodytes
Q1XHU0
518
59727
Y481
V
T
D
R
S
H
I
Y
T
F
T
D
T
F
T
Rhesus Macaque
Macaca mulatta
Q0PF16
497
57280
G462
F
F
N
I
T
N
H
G
F
L
I
Y
K
F
S
Dog
Lupus familis
XP_546929
487
55202
Y451
A
D
F
Q
G
K
L
Y
P
I
L
D
T
C
W
Cat
Felis silvestris
Mouse
Mus musculus
Q810I2
483
54589
K448
F
Q
A
D
F
Q
G
K
L
Y
P
I
L
D
T
Rat
Rattus norvegicus
Q810I1
483
54701
F445
L
Y
T
F
Q
A
D
F
Q
G
K
L
Y
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509541
527
60558
Y486
E
L
G
E
V
S
F
Y
N
M
N
D
R
S
H
Chicken
Gallus gallus
XP_415709
492
55730
Y452
A
E
F
Q
G
Q
L
Y
P
I
V
D
L
C
W
Frog
Xenopus laevis
Q6PGR9
477
54096
F441
N
L
K
L
L
Y
T
F
N
E
R
F
S
G
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
25.5
89.1
N.A.
87.2
86.6
N.A.
29.6
60.7
33
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.6
44.6
94.4
N.A.
92.1
91.9
N.A.
46.2
77.8
55.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
0
100
N.A.
0
0
N.A.
13.3
73.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
13.3
100
N.A.
6.6
6.6
N.A.
26.6
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% C
% Asp:
0
23
12
12
0
0
12
0
0
0
0
56
0
12
0
% D
% Glu:
12
12
0
12
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
23
12
34
12
12
0
12
23
12
12
0
12
0
23
0
% F
% Gly:
0
0
12
0
34
0
12
12
0
12
0
0
0
12
0
% G
% His:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
12
0
0
12
0
0
34
12
12
0
0
12
% I
% Lys:
0
0
12
0
0
23
0
12
0
0
12
0
12
0
0
% K
% Leu:
12
23
0
12
12
0
34
0
12
12
23
12
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
12
0
12
0
0
12
0
0
23
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
34
0
12
0
0
12
0
% P
% Gln:
0
12
0
34
12
23
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
12
0
12
0
12
% R
% Ser:
0
0
0
0
12
12
0
0
0
0
0
0
12
12
12
% S
% Thr:
0
12
12
0
12
0
12
0
12
0
12
0
34
0
23
% T
% Val:
12
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% W
% Tyr:
0
12
0
0
0
12
0
56
0
12
0
12
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _