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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM219 All Species: 17.88
Human Site: S159 Identified Species: 65.56
UniProt: Q86XT9 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XT9 NP_001077082.1 240 25724 S159 P S S Q P P I S C S E E G A G
Chimpanzee Pan troglodytes XP_510915 240 25805 S159 P S S Q P P I S C S E E G A G
Rhesus Macaque Macaca mulatta XP_001106058 240 25748 S159 P S S Q P P I S C S E E G A G
Dog Lupus familis XP_536912 240 25722 S159 P S S Q P P I S C S E E G A G
Cat Felis silvestris
Mouse Mus musculus Q9D123 240 25554 S159 P S S Q P P I S C S E E G V G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511147 120 12490 F40 A G L G L G S F V H F H G A G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001096591 281 30812 N152 L R T D V P N N Q T P A G T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.1 92 N.A. 83.7 N.A. N.A. 30.8 N.A. N.A. 28.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 99.1 95 N.A. 89.5 N.A. N.A. 38.3 N.A. N.A. 44.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 20 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 20 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 0 0 15 0 72 0 % A
% Cys: 0 0 0 0 0 0 0 0 72 0 0 0 0 0 0 % C
% Asp: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 72 72 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 15 0 0 15 0 0 0 0 % F
% Gly: 0 15 0 15 0 15 0 0 0 0 0 0 100 0 86 % G
% His: 0 0 0 0 0 0 0 0 0 15 0 15 0 0 0 % H
% Ile: 0 0 0 0 0 0 72 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 15 0 15 0 15 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 15 0 0 0 0 0 0 0 % N
% Pro: 72 0 0 0 72 86 0 0 0 0 15 0 0 0 15 % P
% Gln: 0 0 0 72 0 0 0 0 15 0 0 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 72 72 0 0 0 15 72 0 72 0 0 0 0 0 % S
% Thr: 0 0 15 0 0 0 0 0 0 15 0 0 0 15 0 % T
% Val: 0 0 0 0 15 0 0 0 15 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _