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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM219
All Species:
14.55
Human Site:
T105
Identified Species:
53.33
UniProt:
Q86XT9
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XT9
NP_001077082.1
240
25724
T105
P
D
R
N
K
T
R
T
F
Q
A
T
V
L
G
Chimpanzee
Pan troglodytes
XP_510915
240
25805
T105
P
D
R
N
K
T
R
T
F
Q
A
T
V
L
G
Rhesus Macaque
Macaca mulatta
XP_001106058
240
25748
I105
P
D
R
N
K
T
R
I
F
Q
A
T
V
L
G
Dog
Lupus familis
XP_536912
240
25722
T105
P
E
G
N
K
T
Q
T
F
Q
A
T
V
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D123
240
25554
T105
P
D
R
N
K
T
Q
T
F
Q
A
K
I
H
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511147
120
12490
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001096591
281
30812
T98
Q
T
N
I
S
T
R
T
T
H
V
S
L
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
92
N.A.
83.7
N.A.
N.A.
30.8
N.A.
N.A.
28.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.1
95
N.A.
89.5
N.A.
N.A.
38.3
N.A.
N.A.
44.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
73.3
N.A.
N.A.
0
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
72
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
72
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
0
15
0
% H
% Ile:
0
0
0
15
0
0
0
15
0
0
0
0
15
0
0
% I
% Lys:
0
0
0
0
72
0
0
0
0
0
0
15
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
15
72
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
72
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
29
0
0
72
0
0
0
0
0
% Q
% Arg:
0
0
58
0
0
0
58
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
15
0
0
0
0
0
0
15
0
0
0
% S
% Thr:
0
15
0
0
0
86
0
72
15
0
0
58
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
15
0
58
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _