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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC6
All Species:
16.97
Human Site:
S15
Identified Species:
33.94
UniProt:
Q86XW9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XW9
NP_835231.1
330
36856
S15
I
A
L
Q
V
N
I
S
T
Q
E
L
W
E
E
Chimpanzee
Pan troglodytes
XP_001151254
330
36837
S15
I
A
L
Q
V
N
I
S
T
Q
E
L
W
E
E
Rhesus Macaque
Macaca mulatta
XP_001114574
330
36832
S15
I
A
L
Q
V
N
I
S
T
Q
E
L
W
E
E
Dog
Lupus familis
XP_542805
551
60809
S193
I
A
L
Q
V
N
I
S
T
Q
E
L
W
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
N15
V
Q
L
Q
S
V
V
N
S
Q
N
L
W
D
E
Rat
Rattus norvegicus
Q715S9
587
67293
N15
V
Q
L
Q
S
V
V
N
S
Q
N
L
W
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
N15
I
P
L
Q
V
T
I
N
N
Q
E
L
W
E
E
Chicken
Gallus gallus
XP_426021
577
65924
C15
I
Q
L
Q
T
T
V
C
N
Q
N
E
W
D
E
Frog
Xenopus laevis
NP_001085047
625
70225
S15
S
S
L
Q
I
A
L
S
N
Q
E
Q
W
E
E
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121486
480
56422
D18
V
E
I
E
S
E
D
D
W
K
Q
L
L
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181827
926
100918
L15
I
S
L
Q
K
E
I
L
N
Q
E
M
W
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
97.5
51
N.A.
23.5
25.2
N.A.
64.8
26
35.6
22.4
N.A.
N.A.
22.7
N.A.
21.6
Protein Similarity:
100
100
99.3
55.7
N.A.
40
39.8
N.A.
75.7
39.6
44
29.7
N.A.
N.A.
40.8
N.A.
27.9
P-Site Identity:
100
100
100
100
N.A.
40
40
N.A.
73.3
40
53.3
0
N.A.
N.A.
13.3
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
73.3
73.3
N.A.
80
53.3
73.3
0
N.A.
N.A.
53.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
0
0
0
0
34
0
% D
% Glu:
0
9
0
9
0
17
0
0
0
0
59
9
0
59
84
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
59
0
9
0
9
0
50
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% K
% Leu:
0
0
84
0
0
0
9
9
0
0
0
67
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
34
0
25
34
0
25
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
25
0
84
0
0
0
0
0
84
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
17
0
0
25
0
0
42
17
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
17
0
0
34
0
0
0
0
0
0
% T
% Val:
25
0
0
0
42
17
25
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
84
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _