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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC6
All Species:
25.76
Human Site:
S281
Identified Species:
51.52
UniProt:
Q86XW9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XW9
NP_835231.1
330
36856
S281
P
F
N
A
V
H
G
S
R
D
R
E
D
A
D
Chimpanzee
Pan troglodytes
XP_001151254
330
36837
S281
P
F
N
A
V
H
G
S
R
D
R
E
D
A
D
Rhesus Macaque
Macaca mulatta
XP_001114574
330
36832
S281
P
F
N
A
V
H
G
S
Q
D
R
E
D
A
D
Dog
Lupus familis
XP_542805
551
60809
S459
P
F
N
A
V
H
G
S
Q
D
R
D
D
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
S294
E
D
D
A
V
K
V
S
K
L
I
D
I
L
F
Rat
Rattus norvegicus
Q715S9
587
67293
Y375
Y
F
D
N
L
I
G
Y
M
C
S
N
N
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
S281
P
F
N
A
V
H
G
S
E
N
Q
E
Q
A
A
Chicken
Gallus gallus
XP_426021
577
65924
S470
K
D
A
G
F
T
I
S
K
V
K
E
E
A
L
Frog
Xenopus laevis
NP_001085047
625
70225
S281
L
Y
N
A
V
H
G
S
N
D
R
E
Q
A
S
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
E130
T
H
G
S
D
S
I
E
S
A
K
R
E
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121486
480
56422
R397
E
I
F
V
I
I
L
R
R
V
S
E
D
A
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181827
926
100918
A324
K
M
N
A
M
H
G
A
D
S
S
E
T
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
97.5
51
N.A.
23.5
25.2
N.A.
64.8
26
35.6
22.4
N.A.
N.A.
22.7
N.A.
21.6
Protein Similarity:
100
100
99.3
55.7
N.A.
40
39.8
N.A.
75.7
39.6
44
29.7
N.A.
N.A.
40.8
N.A.
27.9
P-Site Identity:
100
100
93.3
80
N.A.
20
13.3
N.A.
66.6
20
66.6
0
N.A.
N.A.
26.6
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
40
40
N.A.
80
40
73.3
20
N.A.
N.A.
33.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
67
0
0
0
9
0
9
0
0
0
75
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
17
17
0
9
0
0
0
9
42
0
17
42
0
25
% D
% Glu:
17
0
0
0
0
0
0
9
9
0
0
67
17
0
0
% E
% Phe:
0
50
9
0
9
0
0
0
0
0
0
0
0
0
17
% F
% Gly:
0
0
9
9
0
0
67
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
59
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
17
17
0
0
0
9
0
9
9
0
% I
% Lys:
17
0
0
0
0
9
0
0
17
0
17
0
0
0
0
% K
% Leu:
9
0
0
0
9
0
9
0
0
9
0
0
0
9
9
% L
% Met:
0
9
0
0
9
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
59
9
0
0
0
0
9
9
0
9
9
0
0
% N
% Pro:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
17
0
9
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
25
0
42
9
0
0
0
% R
% Ser:
0
0
0
9
0
9
0
67
9
9
25
0
0
9
25
% S
% Thr:
9
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
9
59
0
9
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _