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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC6
All Species:
13.64
Human Site:
T305
Identified Species:
27.27
UniProt:
Q86XW9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XW9
NP_835231.1
330
36856
T305
L
K
F
S
D
K
D
T
E
A
P
Q
G
G
E
Chimpanzee
Pan troglodytes
XP_001151254
330
36837
T305
L
K
F
S
D
K
D
T
E
A
P
Q
G
G
E
Rhesus Macaque
Macaca mulatta
XP_001114574
330
36832
T305
L
K
F
S
D
K
D
T
E
A
P
Q
G
G
E
Dog
Lupus familis
XP_542805
551
60809
P483
F
K
F
S
D
E
V
P
E
A
S
L
E
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
S433
N
Q
F
Y
G
S
S
S
K
A
A
A
E
K
E
Rat
Rattus norvegicus
Q715S9
587
67293
S434
N
Q
F
Y
G
S
S
S
K
A
A
A
E
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
A305
F
K
V
S
D
E
T
A
E
T
K
Q
R
K
T
Chicken
Gallus gallus
XP_426021
577
65924
S536
D
P
E
V
A
K
E
S
C
P
E
S
I
R
A
Frog
Xenopus laevis
NP_001085047
625
70225
L305
F
K
I
S
N
E
S
L
K
E
L
T
S
V
K
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
E153
E
E
W
M
M
R
E
E
P
H
F
R
L
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121486
480
56422
E450
L
E
D
E
M
E
E
E
E
E
Y
Y
E
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181827
926
100918
E373
A
L
K
D
H
K
D
E
M
L
Q
K
I
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
97.5
51
N.A.
23.5
25.2
N.A.
64.8
26
35.6
22.4
N.A.
N.A.
22.7
N.A.
21.6
Protein Similarity:
100
100
99.3
55.7
N.A.
40
39.8
N.A.
75.7
39.6
44
29.7
N.A.
N.A.
40.8
N.A.
27.9
P-Site Identity:
100
100
100
40
N.A.
20
20
N.A.
33.3
6.6
13.3
6.6
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
100
100
100
46.6
N.A.
40
40
N.A.
40
20
40
40
N.A.
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
9
0
50
17
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
9
0
9
9
42
0
34
0
0
0
0
0
0
0
0
% D
% Glu:
9
17
9
9
0
34
25
25
50
17
9
0
34
9
59
% E
% Phe:
25
0
50
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
0
0
25
34
9
% G
% His:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
17
0
0
% I
% Lys:
0
50
9
0
0
42
0
0
25
0
9
9
0
17
9
% K
% Leu:
34
9
0
0
0
0
0
9
0
9
9
9
9
9
0
% L
% Met:
0
0
0
9
17
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
9
9
9
25
0
0
0
0
% P
% Gln:
0
17
0
0
0
0
0
0
0
0
9
34
0
9
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
9
9
9
0
% R
% Ser:
0
0
0
50
0
17
25
25
0
0
9
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
9
25
0
9
0
9
0
9
9
% T
% Val:
0
0
9
9
0
0
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
0
0
0
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _