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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC6
All Species:
19.09
Human Site:
Y269
Identified Species:
38.18
UniProt:
Q86XW9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XW9
NP_835231.1
330
36856
Y269
P
E
S
L
R
A
Q
Y
G
T
E
M
P
F
N
Chimpanzee
Pan troglodytes
XP_001151254
330
36837
Y269
P
E
S
L
R
A
Q
Y
G
T
E
M
P
F
N
Rhesus Macaque
Macaca mulatta
XP_001114574
330
36832
Y269
P
E
S
L
R
A
Q
Y
G
T
E
M
P
F
N
Dog
Lupus familis
XP_542805
551
60809
F447
P
D
S
L
R
A
Q
F
G
T
E
M
P
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
D282
M
D
R
Q
H
M
S
D
Y
C
D
V
E
D
D
Rat
Rattus norvegicus
Q715S9
587
67293
H363
A
R
A
V
C
H
V
H
E
D
E
D
Y
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
Y269
P
G
S
L
R
A
Q
Y
G
T
E
M
P
F
N
Chicken
Gallus gallus
XP_426021
577
65924
I458
A
K
N
H
K
D
E
I
M
Q
K
V
K
D
A
Frog
Xenopus laevis
NP_001085047
625
70225
Y269
P
E
S
L
R
A
Q
Y
G
T
E
V
L
Y
N
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
D118
R
G
K
Y
G
L
T
D
T
R
N
T
T
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121486
480
56422
Y385
D
F
E
R
K
A
K
Y
Q
T
G
N
E
I
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181827
926
100918
F312
P
E
S
L
R
A
Q
F
G
T
D
K
K
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
97.5
51
N.A.
23.5
25.2
N.A.
64.8
26
35.6
22.4
N.A.
N.A.
22.7
N.A.
21.6
Protein Similarity:
100
100
99.3
55.7
N.A.
40
39.8
N.A.
75.7
39.6
44
29.7
N.A.
N.A.
40.8
N.A.
27.9
P-Site Identity:
100
100
100
86.6
N.A.
0
13.3
N.A.
93.3
0
80
0
N.A.
N.A.
20
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
26.6
40
N.A.
93.3
40
93.3
0
N.A.
N.A.
33.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
67
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
17
0
0
0
9
0
17
0
9
17
9
0
17
17
% D
% Glu:
0
42
9
0
0
0
9
0
9
0
59
0
17
0
0
% E
% Phe:
0
9
0
0
0
0
0
17
0
0
0
0
0
50
9
% F
% Gly:
0
17
0
0
9
0
0
0
59
0
9
0
0
0
9
% G
% His:
0
0
0
9
9
9
0
9
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% I
% Lys:
0
9
9
0
17
0
9
0
0
0
9
9
17
0
0
% K
% Leu:
0
0
0
59
0
9
0
0
0
0
0
0
9
0
0
% L
% Met:
9
0
0
0
0
9
0
0
9
0
0
42
0
9
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
59
% N
% Pro:
59
0
0
0
0
0
0
0
0
0
0
0
42
0
0
% P
% Gln:
0
0
0
9
0
0
59
0
9
9
0
0
0
0
0
% Q
% Arg:
9
9
9
9
59
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
59
0
0
0
9
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
9
67
0
9
9
0
0
% T
% Val:
0
0
0
9
0
0
9
0
0
0
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
50
9
0
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _