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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
14.24
Human Site:
S141
Identified Species:
24.1
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
S141
Q
N
G
T
F
K
K
S
T
V
L
Q
L
G
I
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
S142
Q
N
G
T
F
K
K
S
T
V
L
Q
L
G
I
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
S141
Q
N
G
A
F
K
K
S
T
V
L
Q
L
G
I
Dog
Lupus familis
XP_531835
550
62093
S201
Q
N
G
T
F
K
K
S
T
V
L
Q
L
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
L141
Q
N
G
G
F
K
K
L
T
V
L
Q
L
G
I
Rat
Rattus norvegicus
P97633
325
37477
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
S124
L
H
D
K
N
G
N
S
Y
R
F
M
V
M
D
Chicken
Gallus gallus
Q5ZLL1
416
47453
M82
G
D
Y
N
V
M
V
M
E
L
L
G
P
S
L
Frog
Xenopus laevis
Q5BP74
415
47421
V81
E
G
D
Y
N
V
M
V
M
E
L
L
G
P
S
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
A91
E
L
K
F
Y
M
R
A
A
K
P
D
L
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
P156
E
Q
N
G
K
R
L
P
E
G
T
V
Y
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
L136
E
D
I
W
K
K
Y
L
A
C
N
K
K
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
V116
A
D
Q
M
I
N
R
V
E
F
F
H
S
K
S
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
N133
H
R
D
I
K
P
D
N
F
L
M
G
V
G
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
100
93.3
100
N.A.
86.6
0
N.A.
6.6
6.6
6.6
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
0
N.A.
20
26.6
13.3
33.3
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
22
22
0
0
0
8
0
0
0
0
8
0
0
8
% D
% Glu:
29
0
0
0
0
0
0
0
22
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
36
0
0
0
8
8
15
0
0
8
0
% F
% Gly:
8
8
36
15
0
8
0
0
0
8
0
15
8
43
8
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
8
8
0
0
0
0
0
0
0
0
8
36
% I
% Lys:
0
0
8
8
22
43
36
0
0
8
0
8
8
8
0
% K
% Leu:
8
8
0
0
0
0
8
15
0
15
50
8
43
0
15
% L
% Met:
0
0
0
8
0
15
8
8
8
0
8
8
0
8
0
% M
% Asn:
0
36
8
8
15
8
8
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
8
0
8
8
0
% P
% Gln:
36
8
8
0
0
0
0
0
0
0
0
36
0
0
0
% Q
% Arg:
0
8
0
0
0
8
15
0
0
8
0
0
0
8
8
% R
% Ser:
0
0
0
0
0
0
0
36
0
0
0
0
8
8
15
% S
% Thr:
0
0
0
22
0
0
0
0
36
0
8
0
0
0
8
% T
% Val:
0
0
0
0
8
8
8
15
0
36
0
8
15
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
8
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _