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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VRK2 All Species: 19.39
Human Site: S228 Identified Species: 32.82
UniProt: Q86Y07 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86Y07 NP_001123952.1 508 58141 S228 A H K G V A L S R R S D V E I
Chimpanzee Pan troglodytes XP_001157703 509 58316 S229 A H K G V A L S R R S D V E I
Rhesus Macaque Macaca mulatta XP_001112841 506 57805 S228 A H K G V A L S R R S D V E I
Dog Lupus familis XP_531835 550 62093 S288 A H K G V A P S R R S D L E T
Cat Felis silvestris
Mouse Mus musculus Q8BN21 503 58100 S228 A H K G V A P S R R S D V E I
Rat Rattus norvegicus P97633 325 37477 W78 V G I P H I R W Y G Q G K D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512207 479 54436 E211 C P E G I H K E Y K E D P K R
Chicken Gallus gallus Q5ZLL1 416 47453 E169 H Q H I P Y R E N K N L T G T
Frog Xenopus laevis Q5BP74 415 47421 R168 T H Q H I P Y R E N K N L T G
Zebra Danio Brachydanio rerio Q7ZUS1 425 47752 D178 D H E Y V H A D I K A S N L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KRY6 599 65975 R243 A H L G V P T R R A D L E I L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783182 473 53072 T223 H N G T P E F T S I D A H L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 L203 L E S L G Y I L M Y F L K G S
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 T220 W Q G L K A T T K K Q K Y D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 87.5 70.9 N.A. 69.4 21.8 N.A. 41.9 24.7 26.5 40.1 N.A. 30.8 N.A. N.A. 37.4
Protein Similarity: 100 96.2 91.9 78.3 N.A. 79.9 35.4 N.A. 55.3 39.7 41.3 55.7 N.A. 45.9 N.A. N.A. 52.7
P-Site Identity: 100 100 100 80 N.A. 93.3 0 N.A. 13.3 0 6.6 13.3 N.A. 33.3 N.A. N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 6.6 N.A. 40 13.3 33.3 40 N.A. 40 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 21.4 23 N.A.
Protein Similarity: N.A. N.A. N.A. 38.1 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 0 0 0 0 43 8 0 0 8 8 8 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 8 0 0 15 43 0 15 0 % D
% Glu: 0 8 15 0 0 8 0 15 8 0 8 0 8 36 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 15 50 8 0 0 0 0 8 0 8 0 15 15 % G
% His: 15 58 8 8 8 15 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 8 8 15 8 8 0 8 8 0 0 0 8 29 % I
% Lys: 0 0 36 0 8 0 8 0 8 29 8 8 15 8 0 % K
% Leu: 8 0 8 15 0 0 22 8 0 0 0 22 15 15 15 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 8 8 8 8 8 0 0 % N
% Pro: 0 8 0 8 15 15 15 0 0 0 0 0 8 0 0 % P
% Gln: 0 15 8 0 0 0 0 0 0 0 15 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 15 15 43 36 0 0 0 0 15 % R
% Ser: 0 0 8 0 0 0 0 36 8 0 36 8 0 0 8 % S
% Thr: 8 0 0 8 0 0 15 15 0 0 0 0 8 8 15 % T
% Val: 8 0 0 0 50 0 0 0 0 0 0 0 29 0 0 % V
% Trp: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 15 8 0 15 8 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _