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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
11.21
Human Site:
S344
Identified Species:
18.97
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
S344
P
N
S
Q
K
V
D
S
Q
K
A
A
T
K
Q
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
S345
P
N
S
Q
K
V
D
S
Q
K
A
A
T
K
Q
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
T344
P
N
S
Q
K
V
T
T
Q
K
T
E
T
K
N
Dog
Lupus familis
XP_531835
550
62093
P402
P
N
N
Q
K
V
V
P
R
K
A
A
T
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
S344
P
A
Q
Q
K
V
D
S
P
K
A
T
R
K
P
Rat
Rattus norvegicus
P97633
325
37477
N180
I
P
Y
R
E
D
K
N
L
T
G
T
A
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
Q317
Y
T
E
K
P
L
Y
Q
R
L
R
D
I
L
L
Chicken
Gallus gallus
Q5ZLL1
416
47453
Q271
P
D
Y
S
Y
L
R
Q
L
F
R
N
L
F
H
Frog
Xenopus laevis
Q5BP74
415
47421
R270
K
P
D
Y
S
Y
L
R
Q
L
F
R
N
L
F
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
R280
R
D
S
K
L
R
C
R
D
N
I
D
E
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
A389
S
L
D
E
K
I
S
A
S
E
D
D
E
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
G326
R
T
V
L
K
R
E
G
I
K
E
G
S
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S305
S
Q
L
T
A
P
P
S
R
A
L
N
P
A
V
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
N334
D
N
K
S
E
T
F
N
K
I
K
L
L
A
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
100
66.6
73.3
N.A.
60
0
N.A.
0
6.6
6.6
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
73.3
86.6
N.A.
60
26.6
N.A.
20
20
6.6
20
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
8
0
8
29
22
8
15
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
15
0
0
8
22
0
8
0
8
22
0
0
0
% D
% Glu:
0
0
8
8
15
0
8
0
0
8
8
8
15
8
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
8
0
0
15
15
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
8
0
0
8
8
8
0
8
0
0
% I
% Lys:
8
0
8
15
50
0
8
0
8
43
8
0
0
36
0
% K
% Leu:
0
8
8
8
8
15
8
0
15
15
8
8
15
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
36
8
0
0
0
0
15
0
8
0
15
8
0
8
% N
% Pro:
43
15
0
0
8
8
8
8
8
0
0
0
8
0
8
% P
% Gln:
0
8
8
36
0
0
0
15
29
0
0
0
0
0
22
% Q
% Arg:
15
0
0
8
0
15
8
15
22
0
15
8
8
8
0
% R
% Ser:
15
0
29
15
8
0
8
29
8
0
0
0
8
0
0
% S
% Thr:
0
15
0
8
0
8
8
8
0
8
8
15
29
0
0
% T
% Val:
0
0
8
0
0
36
8
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
15
8
8
8
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _