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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
15.45
Human Site:
S406
Identified Species:
26.15
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
S406
R
R
Q
K
Y
Q
E
S
Q
E
P
L
N
E
V
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
S407
R
R
Q
K
Y
Q
E
S
Q
E
P
L
N
E
V
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
S406
I
R
E
K
Y
Q
E
S
Q
E
L
L
N
E
A
Dog
Lupus familis
XP_531835
550
62093
R459
A
Q
E
S
T
R
R
R
Q
K
Y
Y
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
Y401
R
T
R
K
I
H
E
Y
S
D
I
F
S
E
M
Rat
Rattus norvegicus
P97633
325
37477
E234
A
T
K
K
Q
K
Y
E
K
I
S
E
K
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
S385
R
L
G
E
F
N
F
S
H
D
P
N
H
C
L
Chicken
Gallus gallus
Q5ZLL1
416
47453
T325
G
Q
L
R
G
S
A
T
R
A
L
P
P
G
P
Frog
Xenopus laevis
Q5BP74
415
47421
R324
H
T
R
N
P
A
V
R
G
L
P
S
T
A
S
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
S334
Q
G
L
K
S
I
G
S
T
D
D
K
K
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
R472
P
Q
T
P
T
A
A
R
L
R
T
P
N
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
A381
D
K
P
G
P
S
G
A
A
S
P
R
A
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
P359
S
G
N
I
S
N
Q
P
T
S
S
S
A
R
D
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
Q403
Q
Q
P
Q
Q
Q
V
Q
S
S
Q
P
Q
P
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
100
73.3
6.6
N.A.
26.6
6.6
N.A.
20
0
6.6
13.3
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
80
33.3
N.A.
53.3
40
N.A.
53.3
26.6
13.3
26.6
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
15
15
8
8
8
0
0
15
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
22
8
0
0
0
15
% D
% Glu:
0
0
15
8
0
0
29
8
0
22
0
8
8
29
8
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
8
15
8
8
8
0
15
0
8
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% H
% Ile:
8
0
0
8
8
8
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
8
8
43
0
8
0
0
8
8
0
8
15
8
8
% K
% Leu:
0
8
15
0
0
0
0
0
8
8
15
22
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
0
8
8
0
15
0
0
0
0
0
8
29
0
0
% N
% Pro:
8
0
15
8
15
0
0
8
0
0
36
22
8
8
15
% P
% Gln:
15
29
15
8
15
29
8
8
29
0
8
0
8
0
8
% Q
% Arg:
29
22
15
8
0
8
8
22
8
8
0
8
0
8
0
% R
% Ser:
8
0
0
8
15
15
0
36
15
22
15
15
8
8
8
% S
% Thr:
0
22
8
0
15
0
0
8
15
0
8
0
8
0
0
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
22
0
8
8
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _