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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
17.27
Human Site:
S428
Identified Species:
29.23
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
S428
S
Y
T
Q
F
P
N
S
F
Y
E
P
H
Q
D
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
S429
S
Y
T
Q
F
P
S
S
F
Y
E
P
H
Q
D
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
S428
N
Y
R
Q
F
P
N
S
F
Y
E
P
H
Q
D
Dog
Lupus familis
XP_531835
550
62093
S481
S
S
S
Q
Q
A
S
S
I
Q
F
P
N
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
S423
S
Y
M
S
F
Q
G
S
Y
C
K
P
Y
L
D
Rat
Rattus norvegicus
P97633
325
37477
F256
C
K
G
F
P
A
E
F
A
M
Y
L
N
Y
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
P407
S
L
P
V
Y
P
L
P
V
P
L
P
T
G
N
Chicken
Gallus gallus
Q5ZLL1
416
47453
P347
R
L
R
N
V
A
E
P
M
A
S
T
P
T
S
Frog
Xenopus laevis
Q5BP74
415
47421
L346
E
V
T
P
S
T
P
L
T
P
T
S
H
T
A
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
T356
T
S
L
P
S
V
K
T
P
K
R
K
K
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
G494
S
L
R
G
R
P
G
G
K
T
V
I
N
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
P403
A
K
E
P
V
K
S
P
V
R
S
P
L
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S381
L
F
A
Q
S
A
G
S
S
R
R
V
T
A
V
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
Y425
P
N
G
Q
R
P
N
Y
Y
P
E
P
L
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
93.3
86.6
26.6
N.A.
40
0
N.A.
20
0
13.3
0
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
46.6
N.A.
60
6.6
N.A.
33.3
0
13.3
20
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
29
0
0
8
8
0
0
0
15
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
36
% D
% Glu:
8
0
8
0
0
0
15
0
0
0
29
0
0
0
8
% E
% Phe:
0
8
0
8
29
0
0
8
22
0
8
0
0
0
8
% F
% Gly:
0
0
15
8
0
0
22
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% I
% Lys:
0
15
0
0
0
8
8
0
8
8
8
8
8
0
0
% K
% Leu:
8
22
8
0
0
0
8
8
0
0
8
8
15
15
0
% L
% Met:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
8
0
8
0
0
22
0
0
0
0
0
22
0
8
% N
% Pro:
8
0
8
22
8
43
8
22
8
22
0
58
8
0
0
% P
% Gln:
0
0
0
43
8
8
0
0
0
8
0
0
0
29
8
% Q
% Arg:
8
0
22
0
15
0
0
0
0
15
15
0
0
0
0
% R
% Ser:
43
15
8
8
22
0
22
43
8
0
15
8
0
8
8
% S
% Thr:
8
0
22
0
0
8
0
8
8
8
8
8
15
15
0
% T
% Val:
0
8
0
8
15
8
0
0
15
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
29
0
0
8
0
0
8
15
22
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _