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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
11.82
Human Site:
S445
Identified Species:
20
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
S445
S
P
D
I
F
K
K
S
R
S
P
S
W
Y
K
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
S446
S
P
D
I
F
K
K
S
R
S
P
S
W
Y
K
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
S445
S
P
D
I
F
K
K
S
R
S
P
S
W
Y
K
Dog
Lupus familis
XP_531835
550
62093
P498
P
Y
Q
D
F
T
R
P
D
I
V
N
N
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
P440
R
R
D
P
I
R
K
P
R
S
L
P
R
Y
R
Rat
Rattus norvegicus
P97633
325
37477
D273
L
R
F
E
E
A
P
D
Y
M
Y
L
R
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
P424
P
G
S
S
S
Q
V
P
P
P
T
L
T
T
D
Chicken
Gallus gallus
Q5ZLL1
416
47453
P364
Q
Q
S
G
N
T
S
P
R
A
I
S
R
V
D
Frog
Xenopus laevis
Q5BP74
415
47421
M363
S
P
R
P
V
S
G
M
E
R
E
R
K
V
S
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
D373
G
Q
S
A
D
E
T
D
S
T
P
A
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
T511
P
Q
P
R
S
K
K
T
Y
E
F
N
F
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
L420
I
V
T
T
P
G
A
L
Q
K
K
A
S
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S398
S
R
D
N
F
P
G
S
E
E
L
L
Q
R
S
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
Q442
Q
R
D
S
Q
E
Q
Q
Q
Q
V
P
M
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
100
100
6.6
N.A.
33.3
0
N.A.
0
13.3
13.3
6.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
46.6
0
N.A.
6.6
20
13.3
33.3
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
0
0
8
0
15
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
43
8
8
0
0
15
8
0
0
0
0
0
15
% D
% Glu:
0
0
0
8
8
15
0
0
15
15
8
0
0
8
0
% E
% Phe:
0
0
8
0
36
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
8
8
0
8
0
8
15
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
22
8
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
29
36
0
0
8
8
0
15
8
22
% K
% Leu:
8
0
0
0
0
0
0
8
0
0
15
22
0
0
15
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
0
15
8
0
0
% N
% Pro:
22
29
8
15
8
8
8
29
8
8
29
15
0
0
0
% P
% Gln:
15
22
8
0
8
8
8
8
15
8
0
0
8
8
0
% Q
% Arg:
8
29
8
8
0
8
8
0
36
8
0
8
22
15
22
% R
% Ser:
36
0
22
15
15
8
8
29
8
29
0
29
8
8
15
% S
% Thr:
0
0
8
8
0
15
8
8
0
8
8
0
8
8
8
% T
% Val:
0
8
0
0
8
0
8
0
0
0
15
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
15
0
8
0
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _