KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
19.39
Human Site:
T327
Identified Species:
32.82
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
T327
L
G
P
L
D
F
S
T
K
G
Q
S
I
N
V
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
T328
L
G
P
L
D
F
S
T
K
G
Q
S
I
N
V
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
T327
L
G
S
L
D
F
S
T
E
G
Q
S
I
N
V
Dog
Lupus familis
XP_531835
550
62093
T385
L
G
P
L
D
F
Y
T
R
G
E
S
V
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
T327
L
G
P
L
E
F
S
T
K
V
Q
S
V
H
V
Rat
Rattus norvegicus
P97633
325
37477
K163
I
D
F
G
L
A
K
K
Y
R
D
N
R
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
K300
N
K
P
D
E
I
A
K
Y
L
E
T
V
K
L
Chicken
Gallus gallus
Q5ZLL1
416
47453
F254
E
F
S
T
Y
L
N
F
C
R
S
L
R
F
D
Frog
Xenopus laevis
Q5BP74
415
47421
N253
S
E
F
A
T
Y
L
N
F
C
R
S
L
R
F
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
E263
L
C
S
R
L
P
W
E
D
K
L
Q
D
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
K372
A
A
T
A
R
K
A
K
K
I
D
S
P
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
P309
K
L
K
Y
D
E
E
P
D
Y
N
K
L
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
F288
G
F
Q
F
D
Y
V
F
D
W
T
I
L
K
Y
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
S317
K
G
D
L
N
A
N
S
N
A
A
S
A
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
100
86.6
73.3
N.A.
73.3
0
N.A.
6.6
0
6.6
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
13.3
N.A.
46.6
6.6
26.6
13.3
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
15
0
15
15
0
0
8
8
0
8
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
8
8
8
43
0
0
0
22
0
15
0
8
0
8
% D
% Glu:
8
8
0
0
15
8
8
8
8
0
15
0
0
0
0
% E
% Phe:
0
15
15
8
0
36
0
15
8
0
0
0
0
8
8
% F
% Gly:
8
43
0
8
0
0
0
0
0
29
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
8
0
8
22
0
0
% I
% Lys:
15
8
8
0
0
8
8
22
29
8
0
8
0
15
0
% K
% Leu:
43
8
0
43
15
8
8
0
0
8
8
8
22
0
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
15
8
8
0
8
8
0
29
8
% N
% Pro:
0
0
36
0
0
8
0
8
0
0
0
0
8
8
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
29
8
0
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
8
15
8
0
15
15
8
% R
% Ser:
8
0
22
0
0
0
29
8
0
0
8
58
0
8
0
% S
% Thr:
0
0
8
8
8
0
0
36
0
0
8
8
0
8
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
0
22
8
36
% V
% Trp:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
15
8
0
15
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _