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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
20.3
Human Site:
Y156
Identified Species:
34.36
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
Y156
R
M
L
D
V
L
E
Y
I
H
E
N
E
Y
V
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
Y157
R
M
L
D
V
L
E
Y
I
H
E
N
E
Y
V
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
Y156
R
M
L
D
V
L
E
Y
I
H
E
N
E
Y
V
Dog
Lupus familis
XP_531835
550
62093
Y216
R
M
L
D
V
L
E
Y
I
H
E
N
E
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
Y156
R
M
L
D
V
L
E
Y
I
H
E
N
E
Y
V
Rat
Rattus norvegicus
P97633
325
37477
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
K139
R
F
G
T
D
L
Q
K
V
Y
E
A
N
A
K
Chicken
Gallus gallus
Q5ZLL1
416
47453
S97
E
D
L
F
N
F
C
S
R
K
F
S
L
K
T
Frog
Xenopus laevis
Q5BP74
415
47421
C96
L
E
D
L
F
N
F
C
S
R
K
F
S
L
K
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
M106
A
W
M
K
S
K
K
M
E
Y
L
G
V
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
Y171
A
I
Q
M
L
D
V
Y
Q
Y
M
H
S
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
A151
P
G
L
V
F
A
L
A
I
Q
I
L
D
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
P131
F
L
H
R
D
L
K
P
D
N
F
L
M
G
L
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
I148
R
G
S
T
V
H
V
I
D
F
G
L
S
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
20
6.6
0
0
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
40
13.3
6.6
20
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
8
0
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
36
15
8
0
0
15
0
0
0
8
0
0
% D
% Glu:
8
8
0
0
0
0
36
0
8
0
43
0
36
0
0
% E
% Phe:
8
8
0
8
15
8
8
0
0
8
15
8
0
0
0
% F
% Gly:
0
15
8
0
0
0
0
0
0
0
8
8
0
8
8
% G
% His:
0
0
8
0
0
8
0
0
0
36
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
43
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
15
8
0
8
8
0
0
15
29
% K
% Leu:
8
8
50
8
8
50
8
0
0
0
8
22
8
8
15
% L
% Met:
0
36
8
8
0
0
0
8
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
8
0
36
8
8
0
% N
% Pro:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
8
0
0
0
8
0
8
8
0
0
0
0
0
% Q
% Arg:
50
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
0
8
0
8
0
0
8
8
0
0
8
22
8
0
% S
% Thr:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
8
43
0
15
0
8
0
0
0
8
0
36
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
22
0
0
0
36
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _