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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
19.39
Human Site:
Y162
Identified Species:
32.82
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
Y162
E
Y
I
H
E
N
E
Y
V
H
G
D
I
K
A
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
Y163
E
Y
I
H
E
N
E
Y
V
H
G
D
I
K
A
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
Y162
E
Y
I
H
E
N
E
Y
V
H
G
D
I
K
A
Dog
Lupus familis
XP_531835
550
62093
Y222
E
Y
I
H
E
N
E
Y
V
H
G
D
I
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
Y162
E
Y
I
H
E
N
E
Y
V
H
G
D
I
K
A
Rat
Rattus norvegicus
P97633
325
37477
I12
S
G
S
K
A
E
F
I
V
G
G
K
Y
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
A145
Q
K
V
Y
E
A
N
A
K
K
F
S
R
K
T
Chicken
Gallus gallus
Q5ZLL1
416
47453
K103
C
S
R
K
F
S
L
K
T
V
L
L
L
A
D
Frog
Xenopus laevis
Q5BP74
415
47421
L102
F
C
S
R
K
F
S
L
K
T
V
L
L
L
A
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
P112
K
M
E
Y
L
G
V
P
K
Y
W
G
S
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
N177
V
Y
Q
Y
M
H
S
N
G
Y
V
H
A
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
S157
L
A
I
Q
I
L
D
S
L
E
Y
L
H
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
G137
K
P
D
N
F
L
M
G
L
G
R
R
A
N
Q
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
K154
V
I
D
F
G
L
S
K
K
Y
R
D
F
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
13.3
0
6.6
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
33.3
13.3
20
20
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
8
0
0
0
0
15
8
43
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
8
0
0
0
0
43
0
8
8
% D
% Glu:
36
0
8
0
43
8
36
0
0
8
0
0
0
8
0
% E
% Phe:
8
0
0
8
15
8
8
0
0
0
8
0
8
0
8
% F
% Gly:
0
8
0
0
8
8
0
8
8
15
43
8
0
8
0
% G
% His:
0
0
0
36
0
8
0
0
0
36
0
8
8
0
0
% H
% Ile:
0
8
43
0
8
0
0
8
0
0
0
0
36
0
0
% I
% Lys:
15
8
0
15
8
0
0
15
29
8
0
8
0
50
0
% K
% Leu:
8
0
0
0
8
22
8
8
15
0
8
22
15
8
15
% L
% Met:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
36
8
8
0
0
0
0
0
15
0
% N
% Pro:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
8
8
0
0
0
0
0
0
15
8
8
0
0
% R
% Ser:
8
8
15
0
0
8
22
8
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
15
% T
% Val:
15
0
8
0
0
0
8
0
43
8
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
43
0
22
0
0
0
36
0
22
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _