KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK2
All Species:
15.45
Human Site:
Y64
Identified Species:
26.15
UniProt:
Q86Y07
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y07
NP_001123952.1
508
58141
Y64
R
H
V
V
K
V
E
Y
Q
E
N
G
P
L
F
Chimpanzee
Pan troglodytes
XP_001157703
509
58316
M64
R
H
V
V
K
V
V
M
D
H
K
E
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001112841
506
57805
Y64
R
H
V
V
K
V
E
Y
Q
E
N
G
P
L
F
Dog
Lupus familis
XP_531835
550
62093
Y124
R
H
V
I
K
V
E
Y
Q
E
N
G
P
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BN21
503
58100
Y64
R
H
V
I
K
L
E
Y
Q
E
N
G
P
L
F
Rat
Rattus norvegicus
P97633
325
37477
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512207
479
54436
Y51
Q
G
G
F
G
C
I
Y
L
A
D
G
N
S
S
Chicken
Gallus gallus
Q5ZLL1
416
47453
L11
R
V
G
N
K
Y
R
L
G
R
K
I
G
S
G
Frog
Xenopus laevis
Q5BP74
415
47421
R10
L
R
V
G
N
R
Y
R
L
G
R
K
I
G
S
Zebra Danio
Brachydanio rerio
Q7ZUS1
425
47752
L20
R
A
P
A
K
R
K
L
A
E
E
F
P
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRY6
599
65975
P80
D
A
V
V
K
C
E
P
H
G
N
G
P
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783182
473
53072
I65
D
G
T
Y
V
I
K
I
E
P
H
E
N
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
K45
K
L
E
N
V
K
T
K
H
P
Q
L
L
Y
E
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
Y58
Y
E
S
R
V
Y
R
Y
L
S
G
G
V
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
87.5
70.9
N.A.
69.4
21.8
N.A.
41.9
24.7
26.5
40.1
N.A.
30.8
N.A.
N.A.
37.4
Protein Similarity:
100
96.2
91.9
78.3
N.A.
79.9
35.4
N.A.
55.3
39.7
41.3
55.7
N.A.
45.9
N.A.
N.A.
52.7
P-Site Identity:
100
46.6
100
93.3
N.A.
86.6
0
N.A.
13.3
13.3
6.6
26.6
N.A.
60
N.A.
N.A.
0
P-Site Similarity:
100
46.6
100
100
N.A.
100
0
N.A.
26.6
13.3
6.6
33.3
N.A.
60
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
0
0
0
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
8
8
0
0
0
36
0
8
36
8
15
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
36
% F
% Gly:
0
15
15
8
8
0
0
0
8
15
8
50
8
22
15
% G
% His:
0
36
0
0
0
0
0
0
15
8
8
0
0
0
0
% H
% Ile:
0
0
0
15
0
8
8
8
0
0
0
8
8
0
8
% I
% Lys:
8
0
0
0
58
8
15
8
0
0
15
8
0
0
0
% K
% Leu:
8
8
0
0
0
8
0
15
22
0
0
8
8
43
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
8
0
0
0
0
0
36
0
15
0
0
% N
% Pro:
0
0
8
0
0
0
0
8
0
15
0
0
43
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
29
0
8
0
0
0
0
% Q
% Arg:
50
8
0
8
0
15
15
8
0
8
8
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
8
0
0
8
22
15
% S
% Thr:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
8
50
29
22
29
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
15
8
43
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _