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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC20B
All Species:
2.42
Human Site:
S208
Identified Species:
4.85
UniProt:
Q86Y33
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y33
NP_001139206.1
519
57266
S208
D
E
S
F
H
L
K
S
S
G
D
I
N
D
S
Chimpanzee
Pan troglodytes
XP_001147536
515
56873
R208
D
E
S
F
H
L
K
R
S
G
D
I
N
D
S
Rhesus Macaque
Macaca mulatta
XP_001097843
519
57456
R208
D
E
S
F
H
L
K
R
S
S
D
I
K
E
S
Dog
Lupus familis
XP_535236
519
57802
R208
D
E
S
F
H
L
K
R
F
G
D
I
D
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ66
499
54797
V200
S
S
G
N
V
L
A
V
A
L
D
N
S
V
Y
Rat
Rattus norvegicus
Q62623
499
54810
V200
S
S
G
N
V
L
A
V
A
L
D
N
S
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423833
485
53706
Y186
T
G
L
R
N
D
Y
Y
L
N
I
L
D
W
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RJ9
700
72369
A387
R
I
W
D
M
S
D
A
N
T
N
S
N
Q
L
Honey Bee
Apis mellifera
XP_624567
512
57052
S208
N
L
I
D
W
S
E
S
N
I
L
A
V
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781780
524
57779
L220
D
W
S
C
H
N
H
L
A
V
A
L
A
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LPL5
481
52359
W182
F
Y
L
N
V
V
D
W
S
S
Q
N
V
L
A
Baker's Yeast
Sacchar. cerevisiae
P53197
566
62803
D232
S
M
S
P
V
R
P
D
S
K
Q
L
L
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
94.4
79.3
N.A.
35
36.2
N.A.
N.A.
45.8
N.A.
N.A.
N.A.
20.2
33.5
N.A.
34.9
Protein Similarity:
100
98
96.3
87.6
N.A.
52.7
53.7
N.A.
N.A.
61.8
N.A.
N.A.
N.A.
35.8
50.4
N.A.
48.8
P-Site Identity:
100
93.3
73.3
73.3
N.A.
13.3
13.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
93.3
80
80
N.A.
26.6
26.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
26.6
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.4
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
9
25
0
9
9
9
9
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
0
17
0
9
17
9
0
0
50
0
17
17
0
% D
% Glu:
0
34
0
0
0
0
9
0
0
0
0
0
0
9
0
% E
% Phe:
9
0
0
34
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
9
17
0
0
0
0
0
0
25
0
0
0
0
0
% G
% His:
0
0
0
0
42
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
9
9
34
0
0
0
% I
% Lys:
0
0
0
0
0
0
34
0
0
9
0
0
9
0
0
% K
% Leu:
0
9
17
0
0
50
0
9
9
17
9
25
9
17
17
% L
% Met:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
25
9
9
0
0
17
9
9
25
25
9
17
% N
% Pro:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
0
9
0
% Q
% Arg:
9
0
0
9
0
9
0
25
0
0
0
0
0
0
0
% R
% Ser:
25
17
50
0
0
17
0
17
42
17
0
9
17
0
42
% S
% Thr:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
34
9
0
17
0
9
0
0
17
17
0
% V
% Trp:
0
9
9
0
9
0
0
9
0
0
0
0
0
9
0
% W
% Tyr:
0
9
0
0
0
0
9
9
0
0
0
0
0
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _