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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR2
All Species:
11.82
Human Site:
S573
Identified Species:
26
UniProt:
Q86Y56
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y56
NP_060272.3
855
93493
S573
L
L
E
R
V
T
A
S
H
L
D
W
T
A
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097048
712
78783
L442
T
A
H
S
P
E
L
L
Q
F
S
V
I
I
T
Dog
Lupus familis
XP_548719
860
94486
T578
L
V
E
W
L
A
A
T
Q
N
D
W
T
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNP2
601
65931
E331
N
L
P
A
E
G
R
E
T
V
I
M
N
Q
I
Rat
Rattus norvegicus
Q4QQT4
601
65988
E331
N
L
P
T
E
G
R
E
T
V
I
M
N
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511774
647
72927
L377
N
C
Y
S
L
E
L
L
Q
F
E
V
V
V
T
Chicken
Gallus gallus
XP_414755
833
93018
S551
L
L
E
W
V
S
V
S
H
D
S
W
T
C
Y
Frog
Xenopus laevis
NP_001090507
839
95164
S552
L
L
D
W
V
S
Q
S
H
N
H
W
T
S
Y
Zebra Danio
Brachydanio rerio
XP_002667597
608
67368
R338
G
C
R
E
L
V
V
R
N
L
S
K
L
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731905
845
96272
D554
W
F
H
L
A
L
Q
D
V
I
N
L
D
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791189
835
94103
S552
V
L
D
S
F
Q
S
S
Y
H
Q
W
T
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.3
77.4
N.A.
20.9
21
N.A.
49.7
57.5
54.5
35.9
N.A.
23.1
N.A.
N.A.
44
Protein Similarity:
100
N.A.
78.5
86.2
N.A.
36.3
36.3
N.A.
61.2
71.9
71.5
48
N.A.
43.8
N.A.
N.A.
63.2
P-Site Identity:
100
N.A.
0
46.6
N.A.
6.6
6.6
N.A.
0
53.3
46.6
6.6
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
N.A.
0
66.6
N.A.
13.3
13.3
N.A.
13.3
66.6
73.3
20
N.A.
20
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
10
19
0
0
0
0
0
0
19
10
% A
% Cys:
0
19
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
19
0
0
0
0
10
0
10
19
0
10
0
0
% D
% Glu:
0
0
28
10
19
19
0
19
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
10
0
0
0
0
19
0
0
0
0
10
% F
% Gly:
10
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
19
0
0
0
0
0
28
10
10
0
0
0
19
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
19
0
10
10
19
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
37
55
0
10
28
10
19
19
0
19
0
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% M
% Asn:
28
0
0
0
0
0
0
0
10
19
10
0
19
10
0
% N
% Pro:
0
0
19
0
10
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
10
19
0
28
0
10
0
0
19
0
% Q
% Arg:
0
0
10
10
0
0
19
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
28
0
19
10
37
0
0
28
0
0
10
0
% S
% Thr:
10
0
0
10
0
10
0
10
19
0
0
0
46
0
19
% T
% Val:
10
10
0
0
28
10
19
0
10
19
0
19
10
19
0
% V
% Trp:
10
0
0
28
0
0
0
0
0
0
0
46
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _