KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR2
All Species:
7.58
Human Site:
T21
Identified Species:
16.67
UniProt:
Q86Y56
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y56
NP_060272.3
855
93493
T21
H
P
A
E
G
A
E
T
A
E
A
V
E
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097048
712
78783
Dog
Lupus familis
XP_548719
860
94486
T18
A
S
P
G
L
A
E
T
A
E
A
A
E
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNP2
601
65931
Rat
Rattus norvegicus
Q4QQT4
601
65988
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511774
647
72927
Chicken
Gallus gallus
XP_414755
833
93018
A50
E
R
P
L
S
S
E
A
V
Q
E
V
F
E
A
Frog
Xenopus laevis
NP_001090507
839
95164
S11
E
G
E
Q
R
A
T
S
D
V
T
K
A
L
A
Zebra Danio
Brachydanio rerio
XP_002667597
608
67368
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731905
845
96272
S41
K
E
A
T
N
S
E
S
A
D
K
I
A
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791189
835
94103
S10
A
P
T
T
E
Q
I
S
E
I
R
Q
A
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.3
77.4
N.A.
20.9
21
N.A.
49.7
57.5
54.5
35.9
N.A.
23.1
N.A.
N.A.
44
Protein Similarity:
100
N.A.
78.5
86.2
N.A.
36.3
36.3
N.A.
61.2
71.9
71.5
48
N.A.
43.8
N.A.
N.A.
63.2
P-Site Identity:
100
N.A.
0
60
N.A.
0
0
N.A.
0
13.3
13.3
0
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
0
60
N.A.
0
0
N.A.
0
33.3
33.3
0
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
19
0
0
28
0
10
28
0
19
10
28
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% D
% Glu:
19
10
10
10
10
0
37
0
10
19
10
0
19
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
10
0
10
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
0
0
0
0
0
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
19
19
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
10
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
10
0
0
10
19
0
28
0
0
0
0
0
0
19
% S
% Thr:
0
0
10
19
0
0
10
19
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
10
0
19
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _