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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
16.36
Human Site:
S258
Identified Species:
30
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S258
S
L
I
D
L
A
G
S
E
R
A
S
S
T
H
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
G240
K
Q
Q
D
R
V
P
G
L
T
Q
A
V
Q
V
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
S258
S
L
I
D
L
A
G
S
E
R
A
S
S
T
H
Dog
Lupus familis
XP_548055
762
82876
S191
G
V
M
V
Q
G
L
S
F
H
Q
P
T
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
G242
K
Q
Q
D
R
V
P
G
L
T
Q
A
L
R
V
Rat
Rattus norvegicus
Q4KLL9
826
91176
G242
K
Q
Q
D
R
V
P
G
L
T
Q
A
L
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
A220
Q
H
P
T
D
A
N
A
T
S
S
R
S
H
A
Frog
Xenopus laevis
Q7ZXX2
997
114958
S254
F
M
I
D
L
A
G
S
E
R
A
S
Q
T
Q
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
S260
S
L
I
D
L
A
G
S
E
R
A
S
A
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
T242
I
T
E
R
K
T
D
T
K
R
T
V
K
L
S
Honey Bee
Apis mellifera
XP_001119963
717
81330
Y146
I
C
S
L
L
D
G
Y
N
C
S
V
F
A
Y
Nematode Worm
Caenorhab. elegans
P46873
699
78760
K128
T
A
T
T
E
N
V
K
F
L
V
H
C
S
Y
Sea Urchin
Strong. purpuratus
P46872
699
78679
F128
P
N
S
F
A
H
I
F
G
H
I
A
K
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
6.6
100
6.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
73.3
86.6
N.A.
6.6
13.3
0
0
P-Site Similarity:
100
13.3
100
33.3
N.A.
13.3
13.3
N.A.
N.A.
26.6
80
100
N.A.
20
26.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
39
0
8
0
0
31
31
8
8
16
% A
% Cys:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
0
0
0
54
8
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
31
0
0
0
0
8
0
% E
% Phe:
8
0
0
8
0
0
0
8
16
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
8
39
24
8
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
0
16
0
8
0
8
16
% H
% Ile:
16
0
31
0
0
0
8
0
0
0
8
0
0
0
0
% I
% Lys:
24
0
0
0
8
0
0
8
8
0
0
0
16
0
0
% K
% Leu:
0
24
0
8
39
0
8
0
24
8
0
0
16
8
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
8
0
8
0
0
0
0
0
8
% N
% Pro:
8
0
8
0
0
0
24
0
0
0
0
8
0
0
0
% P
% Gln:
8
24
24
0
8
0
0
0
0
0
31
0
8
8
16
% Q
% Arg:
0
0
0
8
24
0
0
0
0
39
0
8
0
16
0
% R
% Ser:
24
0
16
0
0
0
0
39
0
8
16
31
24
16
8
% S
% Thr:
8
8
8
16
0
8
0
8
8
24
8
0
8
31
0
% T
% Val:
0
8
0
8
0
24
8
0
0
0
8
16
8
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _